A synthetic peptide for use as a blocking control in assays to test for specificity of SIRT4 antibody, Alternative Names: SIRT4 control peptide, SIRT4 antibody Blocking Peptide, Anti-SIRT4 Blocking Peptide, sirtuin, silent mating type information regulation 2 homolog 4, S. cerevisiae Blocking Peptide, MGC130046 Blocking Peptide, MGC130047 Blocking Peptide, MGC57437 Blocking Peptide, SIR2L4 Blocking Peptide, sirtuin 4 Blocking Peptide, SIRT4, SIRT-4, SIRT 4, SIRT-4 Blocking Peptide, SIRT 4 Blocking Peptide
SIRT4 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT4 is included in class IV of the sirtuin family.