A synthetic peptide for use as a blocking control in assays to test for specificity of HIST1 H1 antibody, Alternative Names: HIST1H1C control peptide, HIST1H1C antibody Blocking Peptide, Anti-HIST1H1C Blocking Peptide, Histone Cluster 1 H1C Blocking Peptide, H1.2 Blocking Peptide, H1F2 Blocking Peptide, MGC3992 Blocking Peptide, HIST1, HIST-1, HIST 1, HIST-1 Blocking Peptide, HIST 1 Blocking Peptide
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.