A synthetic peptide for use as a blocking control in assays to test for specificity of MECR antibody, Alternative Names: MECR control peptide, MECR antibody Blocking Peptide, Anti-MECR Blocking Peptide, mitochondrial trans-2-enoyl-CoA reductase Blocking Peptide, CGI-63 Blocking Peptide, FASN2B Blocking Peptide, NRBF1 Blocking Peptide
纯化方法
The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
MECR catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. It may have a role in the mitochondrial synthesis of fatty acids.