Histone Deacetylase 3 (HDAC3) (C-Term) Peptide
HDAC3
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all HDAC3 products
- HDAC3 (Histone Deacetylase 3 (HDAC3))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- IHDVPADLLT YDRTDEADAE ERGPEENYSR PEAPNEFYDG DHDNDKESDV
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- HDAC3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- HDAC3 (Histone Deacetylase 3 (HDAC3))
- 背景
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Alias Symbols: HD3, RPD3, RPD3-2
Protein Size: 428 - 基因ID
- 8841
- NCBI登录号
- NM_003883, NP_003874
- UniProt
- O15379
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