Agouti Signaling Protein (ASIP) (Middle Region) Peptide
ASIP
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all ASIP products
- ASIP (Agouti Signaling Protein (ASIP))
- 蛋白结构域
- Middle Region
- 宿主
- 人
- 资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- CFFTANSHLP PEEKLRDDRS LRSNSSVNLL DVPSVSIVAL NKKSKQIGRK
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- ASIP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- ASIP (Agouti Signaling Protein (ASIP))
- 背景
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In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.
Alias Symbols: ASP, AGSW, AGTI, AGTIL, SHEP9
Protein Size: 132 - 基因ID
- 434
- NCBI登录号
- NM_001672, NP_001663
- UniProt
- P42127
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