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Caspase Recruitment Domain Family, Member 11 (CARD11) (Middle Region) Peptide

CARD11 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5511030
发货至: 中国
  • 抗原 See all CARD11 products
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    SPRLSRASFL FGQLLQFVSR SENKYKRMNS NERVRIISGS PLGSLARSSL
    产品特性
    This is a synthetic peptide designed for use in combination with anti-CARD11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    背景
    The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

    Alias Symbols: PPBL, BENTA, BIMP3, IMD11, CARMA1

    Protein Size: 1171
    基因ID
    84433
    NCBI登录号
    NM_032415, NP_115791
    UniProt
    Q8TES3
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