Rabbit Anti-CDC2 (Phospho-Tyr15) Polyclonal Antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
纯度
> 95 %
限制
仅限研究用
储存条件
-20 °C
Li, Wu, Wang, Wu, Song, Xian, Yuan, Pei, Shang: "Resolvin D1 promotes the interleukin-4-induced alternative activation in BV-2 microglial cells." in: Journal of neuroinflammation, Vol. 11, pp. 72, (2014) (PubMed).
Soehnlein, Zernecke, Eriksson, Rothfuchs, Pham, Herwald, Bidzhekov, Rottenberg, Weber, Lindbom: "Neutrophil secretion products pave the way for inflammatory monocytes." in: Blood, Vol. 112, Issue 4, pp. 1461-71, (2008) (PubMed).
抗原
N-Boc-Phe-Leu-Phe-Leu-Phe
物质类
Peptide
背景
As a well-known FPR antagonist, formyl peptide receptor antagonist Boc-Phe-Leu-Phe-Leu-Phe is used extensively in FPR research. In regard to neutrophils, it was found that treatment of mice with Boc-PLPLP results in 40% reduction in neutrophil counts recovered in bronchoalveolar lavage fluid, compared with infected mice receiving placebo.