GTP Cyclohydrolase 1 (GCH1) (N-Term) Peptide
GCH1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all GCH1 products
- GCH1 (GTP Cyclohydrolase 1 (GCH1))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- PPRPEAKSAQ PADGWKGERP RSEEDNELNL PNLAAAYSSI LSSLGENPQR
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-GCH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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GTP Cyclohydrolase 1 (GCH1) peptide
GCH1 适用: 人, 小鼠, 大鼠 宿主: 合成 BP, Imm
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- GCH1 (GTP Cyclohydrolase 1 (GCH1))
- 背景
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This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.
Protein Size: 250 - 分子量
- 27 kDa
- 基因ID
- 2643
- UniProt
- P30793
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