This is a synthetic peptide designed for use in combination with anti-CHEK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
CHEK1 is a serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. It may also negatively regulate cell cycle progression during unperturbed cell cycles.