This is a synthetic peptide designed for use in combination with anti-LEF1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1).
Alias Symbols: DKFZp586H0919, FLJ46390, TCF1ALPHA
Protein Interaction Partner: CTNNB1,SMAD3,TLE1,ALX4,CDX1,CTNNB1,EP300,KPNA1,KPNA2,MITF,NLK,NOTCH1,PIAS4,PITX2,RUNX2,SMAD1,SMAD2,SMAD3,SMAD4,SUMO2,THOC4,TLE1,UBTF,CTNNB1,DACT1,DAZAP2,E2F1,EP300,HDAC1,Kpna1,Kpna2,MITF,NLK,NOTCH1,PIAS4,RUVBL1,SMAD2,SMAD3,SMAD4,SMAD7,THOC4,TLE1,UBTF,ZBTB