SARS-CoV-2 Spike (C-Term) Peptide
(2 references)-
- 抗原 See all SARS-CoV-2 Spike products
- SARS-CoV-2 Spike
- 蛋白结构域
- C-Term
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV)
- 应用范围
- Blocking Peptide (BP)
- 产品特性
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20 amino acids near the carboxy terminus of SARS Spike protein.
Virus
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SARS-CoV-2 Spike peptide
适用: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 合成 InhA
SARS-CoV-2 Spike peptide适用: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 合成 InhA
SARS-CoV-2 Spike peptide (Cy5)适用: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 合成 InhA
SARS-CoV-2 Spike peptide (Cy5)适用: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 合成 InhA
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- 应用备注
- SARS Spike peptide is used for blocking the activity of the SARS Spike.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 200 μg/mL
- 缓冲液
- PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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: "High-throughput fabrication of high aspect ratio Ag/Al nanopillars for optical detection of biomarkers." in: Journal of materials chemistry. B, (2021) (PubMed).
: "Detection of antibodies against SARS-CoV-2 spike protein by gold nanospikes in an opto-microfluidic chip." in: Biosensors & bioelectronics, Vol. 169, pp. 112578, (2020) (PubMed).
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: "High-throughput fabrication of high aspect ratio Ag/Al nanopillars for optical detection of biomarkers." in: Journal of materials chemistry. B, (2021) (PubMed).
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- 抗原
- SARS-CoV-2 Spike
- 别名
- E2 Peptide, E2 glycoprotein precursor Peptide, Surface Glycoprotein Peptide, S Peptide
- 物质类
- Viral Protein
- 背景
- Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak. The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection. The spike protein is the major target for neutralizing antibodies and vaccine development. The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19. The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein .
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