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PEA15 产品

(phosphoprotein Enriched in Astrocytes 15 (PEA15))
This gene encodes a death effector domain-containing protein, which is a major phosphoprotein in astrocytes, and an endogenous substrate for protein kinase C. Studies using knockout mice suggest that this protein may protect astrocytes from TNF-induced apoptosis. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. [provided by RefSeq, Sep 2011].

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Featured PEA15 Categories

PEA15 抗体

High quality antibodies with extensive validation data.

PEA15 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PEA15 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PEA15 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (6)
Cat. No. ABIN7265284
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), FACS
Validations
  • (1)
  • (4)
Cat. No. ABIN652463
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7144769
Quantity 100 μL
Datasheet Datasheet

Recommended PEA15 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380248
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380318
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended PEA15 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314623
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7318180
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1692149
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our PEA15 Products

Kim, Kang: "PKC, AKT and ERK1/2-Mediated Modulations of PARP1, NF-κB and PEA15 Activities Distinctly Regulate Regional Specific Astroglial Responses Following Status Epilepticus." in: Frontiers in molecular neuroscience, Vol. 12, pp. 180, (2019) (PubMed).

Lv, Ma, Zhang, Zheng, Ma, Zhao, Lai, Shen, Wang, Ji: "Quantitative proteomics reveals that PEA15 regulates astroglial A? phagocytosis in an Alzheimer's disease mouse model." in: Journal of proteomics, Vol. 110C, pp. 45-58, (2014) (PubMed).

Peacock, Palmer, Fink, Ip, Pietras, Mui, Chung, Gleave, Cox, Parsons, Peter, Ong: "PTEN loss promotes mitochondrially dependent type II Fas-induced apoptosis via PEA-15." in: Molecular and cellular biology, Vol. 29, Issue 5, pp. 1222-34, (2009) (PubMed).

Synonyms and alternative names related to PEA15

proliferation and apoptosis adaptor protein 15 (PEA15), proliferation and apoptosis adaptor protein 15 (Pea15), phosphoprotein enriched in astrocytes 15 (PEA15), proliferation and apoptosis adaptor protein 15 L homeolog (pea15.L), proliferation and apoptosis adaptor protein 15 (pea15), Astrocytic phosphoprotein PEA-15 (pea15), phosphoprotein enriched in astrocytes 15 (pea15), DKFZp459O1410, HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PEA15, Pea15a, PED

Protein level used designations for PEA15

  • 15 kDa phosphoprotein enriched in astrocytes
  • Phosphoprotein enriched in astrocytes, 15kD
  • astrocytic phosphoprotein PEA-15
  • homolog of mouse MAT-1 oncogene
  • phosphoprotein enriched in diabetes
  • phosphoprotein enriched in astrocytes 15A
  • phosphoprotein enriched in astrocytes 15
  • Astrocytic phosphoprotein PEA-15
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