PDX1 产品
(Pancreatic and Duodenal Homeobox 1 (PDX1))
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The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008].
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Featured PDX1 Categories
PDX1 抗体
High quality antibodies with extensive validation data.
PDX1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PDX1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PDX1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7441508
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (2)
- (4)
Cat. No.
ABIN969554
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (6)
Cat. No.
ABIN3032144
Quantity
0.4 mL
Datasheet
Datasheet
Recommended PDX1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969131
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958375
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4884142
Quantity
96 tests
Datasheet
Datasheet
Recommended PDX1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314593
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7409143
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7409140
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PDX1 Products
: "Low-Level Insulin Content Within Abundant Non-β Islet Endocrine Cells in Long-standing Type 1 Diabetes." in: Diabetes, Vol. 68, Issue 3, pp. 598-608, (2019) (PubMed).: "Possible role of miR-2909 RNomics in arsenic mediated pancreatic β-cell dysfunction." in: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), Vol. 50, pp. 263-267, (2019) (PubMed).
: "Sall2 knockdown exacerbates palmitic acid induced dysfunction and apoptosis of pancreatic NIT-1 beta cells." in: Biomedicine & pharmacotherapy, Vol. 104, pp. 375-382, (2018) (PubMed).
: "Isolation and Characterization of Pancreatic Canine Fetal Cells at the Final Stage of Gestation." in: Anatomical record (Hoboken, N.J. : 2007), (2018) (PubMed).
: "Highly Proliferative α-Cell-Related Islet Endocrine Cells in Human Pancreata." in: Diabetes, Vol. 67, Issue 4, pp. 674-686, (2018) (PubMed).
: "Effect of Wnt Signaling on the Differentiation of Islet β-Cells from Adipose-Derived Stem Cells." in: BioMed research international, Vol. 2017, pp. 2501578, (2017) (PubMed).
: "The Modification of Tet1 in Male Germline Stem Cells and Interact with PCNA, HDAC1 to promote their Self-renewal and Proliferation." in: Scientific reports, Vol. 6, pp. 37414, (2016) (PubMed).
: "Generation of insulin-producing cells from C3H10T1/2 mesenchymal progenitor cells." in: Gene, Vol. 562, Issue 1, pp. 107-16, (2015) (PubMed).
: "Interferon-? Decreases Nuclear Localization of Pdx-1 and Triggers ?-Cell Dysfunction in Chronic Pancreatitis." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 35, Issue 7, pp. 523-9, (2015) (PubMed).
: "Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion." in: Science (New York, N.Y.), Vol. 350, Issue 6261, pp. aac4250, (2015) (PubMed).
Synonyms and alternative names related to PDX1
pancreatic and duodenal homeobox 1 (PDX1), pancreatic and duodenal homeobox 1 (pdx1), pancreatic and duodenal homeobox 1 (Pdx1), pancreatic and duodenal homeobox 1 S homeolog (pdx1.S), GSF, IDX-1, Idx1, IPF-1, IPF1, ipf1, Ipf1, IUF1, MODY4, Mody4, PDX-1, pdx-1, PDX1, STF-1, Stf1, XlHbox-8, xlhbox8, zgc:100874Protein level used designations for PDX1
- IPF-1
- IUF-1
- glucose-sensitive factor
- insulin promoter factor 1, homeodomain transcription factor
- insulin upstream factor 1
- islet/duodenum homeobox-1
- pancreas/duodenum homeobox protein 1
- pancreatic-duodenal homeobox factor 1
- somatostatin transcription factor 1
- somatostatin-transactivating factor 1
- homeodomain protein PDX-1
- pancreatic and duodenum homeobox 1
- pancreatic duodenal homeobox gene 1
- pancreatic and duodenal homeobox 1
- islet/duodenum homeobox 1
- pancreatic and duodenal homeobox gene 1
- IDX-1
- Insulin promoter factor 1
- STF-1
- insulin promotor factor 1
- somatostatin transactivating factor 1
- homeodomain protein PDX1
- Homeobox protein 8
- XlHbox 8 protein
- LOW QUALITY PROTEIN: pancreas/duodenum homeobox protein 1
- Homeodomain protein PDX1
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