PDP 抗体
(Pyruvate Dehydrogenase Phosphatase (PDP))
Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported\; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009].
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PDP 抗体 by 适用
Find PDP 抗体 for a variety of species such as anti-Human PDP, anti-Mouse PDP, anti-Rat PDP. The species listed below are among those available. Click on a link to go to the corresponding products.
PDP 抗体 by 应用范围
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PDP 抗体 by 克隆形成能力
Find available monoclonal or polyclonal PDP 抗体. Click on a link to go to the corresponding products.
PDP 抗体 by 克隆
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
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Application
WB, IHC, IF
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Cat. No.
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Quantity
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Application
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN751843
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN751845
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IF (p), IF (cc)
Validations
Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN911937
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN5009103
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
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Quantity
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Datasheet
Datasheet
Latest Publications for our PDP 抗体
: "Tyr-94 phosphorylation inhibits pyruvate dehydrogenase phosphatase 1 and promotes tumor growth." in: The Journal of biological chemistry, Vol. 289, Issue 31, pp. 21413-22, (2014) (PubMed).Aliases for PDP 抗体
Pyruvate dehydrogenase phosphatase (Pdp) 抗体pyruvate dehydrogenase [acetyl-transferring]-phosphatase 1, mitochondrial (LOC413080) 抗体
pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1) 抗体
pyruvate dehyrogenase phosphatase catalytic subunit 1 (Pdp1) 抗体
pyruvate dehyrogenase phosphatase catalytic subunit 1 (pdp1) 抗体
pyruvate dehyrogenase phosphatase catalytic subunit 1 L homeolog (pdp1.L) 抗体
153332_at 抗体
CG12151 抗体
Dmel\\CG12151 抗体
Gm1024 抗体
im:7157162 抗体
PDH 抗体
PDP 抗体
pdp 抗体
pdp1 抗体
PDPC 抗体
PPM2C 抗体
Ppm2c 抗体
ppm2c 抗体
zgc:174908 抗体
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