电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PDE8B 产品

(phosphodiesterase 8B (PDE8B))

Categories

The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured PDE8B Categories

PDE8B 抗体

High quality antibodies with extensive validation data.

Recommended PDE8B 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Bat, Horse, Human, Monkey
Application IHC (p), IHC
Validations
  • (2)
Cat. No. ABIN213535
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7155168
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN1881646
Quantity 400 μL
Datasheet Datasheet

Recommended PDE8B 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094523
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3131150
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PDE8B Products

Horvath, Faucz, Finkielstain, Nikita, Rothenbuhler, Almeida, Mericq, Stratakis: "Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels." in: Thyroid : official journal of the American Thyroid Association, Vol. 20, Issue 4, pp. 363-7, (2010) (PubMed).

Shields, Freathy, Knight, Hill, Weedon, Frayling, Hattersley, Vaidya: "Phosphodiesterase 8B gene polymorphism is associated with subclinical hypothyroidism in pregnancy." in: The Journal of clinical endocrinology and metabolism, Vol. 94, Issue 11, pp. 4608-12, (2009) (PubMed).

Bimpaki, Nesterova, Stratakis: "Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 161, Issue 1, pp. 153-61, (2009) (PubMed).

Horvath, Giatzakis, Tsang, Greene, Osorio, Boikos, Libè, Patronas, Robinson-White, Remmers, Bertherat, Nesterova, Stratakis: "A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex." in: European journal of human genetics : EJHG, Vol. 16, Issue 10, pp. 1245-53, (2008) (PubMed).

Synonyms and alternative names related to PDE8B

phosphodiesterase 8B (PDE8B), high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (LOC100468338), phosphodiesterase 8B (pde8b), phosphodiesterase 8B (Pde8b), ADSD, B230331L10Rik, C030047E14Rik, PDE8B, PPNAD3, RNPDE8B

Protein level used designations for PDE8B

  • phosphodiesterase 8B
  • high-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
  • high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like
  • 3',5' cyclic nucleotide phosphodiesterase 8B
  • cell proliferation-inducing gene 22 protein
  • high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
  • hsPDE8B
  • cAMP-specific cyclic nucleotide phosphodiesterase PDE8
You are here:
客服