PDE6H 产品
(phosphodiesterase 6H, CGMP-Specific, Cone, gamma (PDE6H))
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This gene encodes the inhibitory (or gamma) subunit of the cone-specific cGMP phosphodiesterase, which is a tetramer composed of two catalytic chains (alpha and beta), and two inhibitory chains (gamma). It is specifically expressed in the retina, and is involved in the transmission and amplification of the visual signal. Mutations in this gene are associated with retinal cone dystrophy type 3A (RCD3A). [provided by RefSeq, Mar 2010].
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Featured PDE6H Categories
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Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124408
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314480
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2728526
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our PDE6H Products
: "A substitution of G to C in the cone cGMP-phosphodiesterase gamma subunit gene found in a distinctive form of cone dystrophy." in: Ophthalmology, Vol. 112, Issue 1, pp. 159-66, (2005) (PubMed).: "Three-dimensional structure of non-activated cGMP phosphodiesterase 6 and comparison of its image with those of activated forms." in: Journal of structural biology, Vol. 139, Issue 1, pp. 27-38, (2002) (PubMed).
: "Isolation and chromosomal localization of the human cone cGMP phosphodiesterase gamma cDNA (PDE6H)." in: Genomics, Vol. 32, Issue 1, pp. 121-4, (1996) (PubMed).
: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).
Synonyms and alternative names related to PDE6H
phosphodiesterase 6H (PDE6H), phosphodiesterase 6H, cGMP-specific, cone, gamma (Pde6h), phosphodiesterase 6H (Pde6h), A930033D18Rik, ACHM6, Pde6g, PDEgamma, RCD3Protein level used designations for PDE6H
- GMP-PDE gamma
- retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
- cone phosphodiesterase 6 gamma
- cone-like cGMP-phosphodiesterase 6 gamma subunit type 2
- phosphodiesterase 6G, cGMP-specific, rod, gamma
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