PDE4A 抗体
(phosphodiesterase 4A, CAMP-Specific (PDE4A))
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].
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PDE4A 抗体 by 适用
Find PDE4A 抗体 for a variety of species such as anti-Human PDE4A, anti-Mouse PDE4A, anti-Rat PDE4A. The species listed below are among those available. Click on a link to go to the corresponding products.
PDE4A 抗体 by 应用范围
Find PDE4A 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.
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PDE4A 抗体 by 抗原表位
Find PDE4A 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
PDE4A 抗体 by 克隆形成能力
Find available monoclonal or polyclonal PDE4A 抗体. Click on a link to go to the corresponding products.
PDE4A 抗体 by 克隆
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Popular PDE4A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, FACS, IHC (p)
Validations
- (7)
Cat. No.
ABIN1500089
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7243706
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN7269302
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, FACS
Validations
- (3)
Cat. No.
ABIN2728496
Quantity
0.1 mL
Datasheet
Datasheet
Reactivity
Elk, Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, IP, ICC, CM
Validations
- (37)
Cat. No.
ABIN2750880
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN948232
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
- (1)
Cat. No.
ABIN518722
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Chicken, Human, Monkey, Mouse, Rat
Application
WB, IHC, ELISA, IF, IP, ICC, CM
Validations
- (13)
Cat. No.
ABIN2747099
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p), IHC (p)
Validations
Cat. No.
ABIN1387127
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
Cat. No.
ABIN1404277
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p)
Validations
Cat. No.
ABIN2805182
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p)
Validations
Cat. No.
ABIN5008528
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p)
Validations
Cat. No.
ABIN1404274
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p)
Validations
Cat. No.
ABIN1404275
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p)
Validations
Cat. No.
ABIN1404276
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our PDE4A 抗体
: "CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine. ..." in: PLoS biology, Vol. 16, Issue 6, pp. e2004408, (2018) (PubMed).: "The Regulatory Role of Rolipram on Inflammatory Mediators and Cholinergic/Adrenergic Stimulation-Induced Signals in Isolated Primary Mouse Submandibular Gland Cells." in: Mediators of inflammation, Vol. 2016, pp. 3745961, (2017) (PubMed).
: "Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol-induced steatosis." in: The Journal of pathology, Vol. 240, Issue 1, pp. 96-107, (2017) (PubMed).
: "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." in: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).
: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).
: "Expression and distribution of phosphodiesterase isoenzymes in the human male urethra." in: Urology, Vol. 85, Issue 4, pp. 964.e1-6, (2015) (PubMed).
: "NCS 613 exhibits anti-inflammatory effects on PBMCs from lupus patients by inhibiting p38 MAPK and NF-κB signalling pathways while reducing proinflammatory cytokine production." in: Canadian journal of physiology and pharmacology, Vol. 91, Issue 5, pp. 353-61, (2014) (PubMed).
: "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." in: Neuroscience, Vol. 263, pp. 1-14, (2014) (PubMed).
: "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." in: Cellular signalling, Vol. 26, Issue 5, pp. 1001-10, (2014) (PubMed).
: "RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects." in: British journal of pharmacology, Vol. 168, Issue 4, pp. 1001-14, (2013) (PubMed).
Aliases for PDE4A 抗体
phosphodiesterase 4A S homeolog (pde4a.S) 抗体phosphodiesterase 4A, cAMP-specific (pde4a) 抗体
phosphodiesterase 4A (PDE4A) 抗体
phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) (PDE4A) 抗体
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (LOC100009247) 抗体
phosphodiesterase 4A (Pde4a) 抗体
phosphodiesterase 4A (pde4a) 抗体
phosphodiesterase 4A, cAMP specific (Pde4a) 抗体
phosphodiesterase 4C (PDE4C) 抗体
phosphodiesterase 4A, cAMP-specific (PDE4A) 抗体
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