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PDE1C 产品

(phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM, Oct 2009].

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Featured PDE1C Categories

PDE1C 抗体

High quality antibodies with extensive validation data.

PDE1C ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PDE1C 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PDE1C 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7146420
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6243943
Quantity 200 μL
Datasheet Datasheet
Reactivity Bat, Cow, Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6741846
Quantity 100 μL
Datasheet Datasheet

Recommended PDE1C ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969260
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969259
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958530
Quantity 96 tests
Datasheet Datasheet

Recommended PDE1C 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
Cat. No. ABIN7197331
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3085620
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3123289
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PDE1C Products

Cesarini, Martini, Vitiani, Gravina, Di Agostino, Graziani, DAlessandris, Pallini, Larocca, Rossi, Jannini, Dolci: "Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome." in: Oncotarget, Vol. 8, Issue 8, pp. 13223-13239, (2017) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Yougbaré, Keravis, Abusnina, Decossas, Schall, Muller, Lugnier: "Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling." in: Biochimica et biophysica acta, Vol. 1842, Issue 7, pp. 916-26, (2014) (PubMed).

Abusnina, Keravis, Yougbaré, Bronner, Lugnier: "Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1." in: Molecular nutrition & food research, Vol. 55, Issue 11, pp. 1677-89, (2012) (PubMed).

Abusnina, Alhosin, Keravis, Muller, Fuhrmann, Bronner, Lugnier: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).

Genders, Bradley, Rattigan, Richards: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).

Ortiz-Capisano, Liao, Ortiz, Beierwaltes: "Calcium-dependent phosphodiesterase 1C inhibits renin release from isolated juxtaglomerular cells." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 297, Issue 5, pp. R1469-76, (2009) (PubMed).

Dong, Zitt, Auriga, Hatzelmann, Epstein: "Inhibition of PDE3, PDE4 and PDE7 potentiates glucocorticoid-induced apoptosis and overcomes glucocorticoid resistance in CEM T leukemic cells." in: Biochemical pharmacology, Vol. 79, Issue 3, pp. 321-9, (2009) (PubMed).

Deplano, Giorgi, Maccarone, Santone, Nuccetelli, Basso, Bisti: "Gene expression and protein localization of calmodulin-dependent phosphodiesterase during ontogenesis of chick retina." in: Journal of neuroscience research, Vol. 86, Issue 5, pp. 1017-23, (2008) (PubMed).

Murray, Patel, Suda, Zhang, Thistlethwaite, Yuan, Insel: "Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 1, pp. L294-303, (2007) (PubMed).

Synonyms and alternative names related to PDE1C

Phosphodiesterase 1c (Pde1c), phosphodiesterase 1C (PDE1C), calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (LOC724389), calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (LOC100019026), phosphodiesterase 1C, calmodulin-dependent b (pde1cb), phosphodiesterase 1C (Pde1c), CG14940, CG14942, CG14943, CG14944, CG31757, CG31758, CG42325, CG44007, Dmel\\CG44007, Dmel_CG14940, Dmel_CG14943, Dmel_CG14944, Dmel_CG31757, Dmel_CG31758, Dmel_CG42325, GB13690, Hcam3, PDE1C, PDE1c

Protein level used designations for PDE1C

  • CG44007-PB
  • CG44007-PC
  • CG44007-PD
  • CG44007-PE
  • CG44007-PG
  • CG44007-PH
  • CG44007-PJ
  • CG44007-PK
  • Pde1c-PB
  • Pde1c-PC
  • Pde1c-PD
  • Pde1c-PE
  • Pde1c-PG
  • Pde1c-PH
  • Pde1c-PJ
  • Pde1c-PK
  • phosphodiesterase 1c
  • phosphodiesterase 1C, calmodulin-dependent 70kDa
  • calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
  • calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C-like
  • cam-PDE 1C
  • cyclic nucleotide phosphodiesterase 1 C
  • phosphodiesterase 1C calmodulin-dependent (70kD)
  • Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A)
  • hCam-3
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