PD-1 产品
(Programmed Cell Death 1 (PDCD1))
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This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008].
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Featured PD-1 Categories
PD-1 抗体
High quality antibodies with extensive validation data.
PD-1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PD-1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PD-1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
FACS, WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
- (2)
- (3)
- (1)
Cat. No.
ABIN735608
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (8)
Cat. No.
ABIN7440431
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS, WB, ELISA
Validations
- (5)
Cat. No.
ABIN7193563
Quantity
100 μL
Datasheet
Datasheet
Recommended PD-1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958801
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Various Species
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN6971295
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969576
Quantity
96 tests
Datasheet
Datasheet
Recommended PD-1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (6)
Cat. No.
ABIN7275419
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (6)
Cat. No.
ABIN7275418
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7275420
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PD-1 Products
: "Conditional PD-1/PD-L1 Probody Therapeutics Induce Comparable Antitumor Immunity but Reduced Systemic Toxicity Compared with Traditional Anti-PD-1/PD-L1 Agents. ..." in: Cancer immunology research, Vol. 9, Issue 12, pp. 1451-1464, (2022) (PubMed).: "Cell-targeted PD-1 agonists that mimic PD-L1 are potent T cell inhibitors." in: JCI insight, Vol. 6, Issue 20, (2021) (PubMed).
: "Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth." in: Molecular therapy oncolytics, Vol. 17, pp. 9-20, (2020) (PubMed).
: "An engineered oncolytic virus expressing PD-L1 inhibitors activates tumor neoantigen-specific T cell responses." in: Nature communications, Vol. 11, Issue 1, pp. 1395, (2020) (PubMed).
: "Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors." in: EMBO molecular medicine, Vol. 12, Issue 6, pp. e11571, (2020) (PubMed).
: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).
: "Evaluation of costimulatory molecules in dogs with B cell high grade lymphoma." in: PLoS ONE, Vol. 13, Issue 7, pp. e0201222, (2019) (PubMed).
: "Immune Activation and Benefit From Avelumab in EBV-Positive Gastric Cancer." in: Journal of the National Cancer Institute, Vol. 110, Issue 3, pp. 316-320, (2019) (PubMed).
: "Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection." in: PLoS pathogens, Vol. 15, Issue 3, pp. e1007311, (2019) (PubMed).
: "Tumor-derived exosomal HMGB1 promotes esophageal squamous cell carcinoma progression through inducing PD1+ TAM expansion." in: Oncogenesis, Vol. 8, Issue 3, pp. 17, (2019) (PubMed).
Synonyms and alternative names related to PD-1
programmed cell death 1 (PDCD1), programmed cell death 1 (Pdcd1), CD279, hPD-1, hPD-l, Ly101, PD-1, PD1, Pdc1, SLEB2Protein level used designations for PD-1
- programmed cell death protein 1
- protein PD-1
- programmed cell death 1
- programmed death 1
- mPD-1
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