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PCSK6 产品

(Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))

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The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Featured PCSK6 Categories

PCSK6 抗体

High quality antibodies with extensive validation data.

Recommended PCSK6 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (5)
Cat. No. ABIN562089
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
  • (3)
Cat. No. ABIN308447
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Horse, Human, Monkey, Rabbit, Rat
Application ELISA, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN461695
Quantity 50 μg
Datasheet Datasheet

Recommended PCSK6 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958854
Quantity 96 tests
Datasheet Datasheet

Recommended PCSK6 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314361
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PCSK6 Products

Ha, Jin, Jorgensen, Zogg, Wei, Singh, Park, Kurahashi, Kim, Baek, Poudrier, Lee, Sanders, Ro: "Transcriptome profiling of subepithelial PDGFRα cells in colonic mucosa reveals several cell-selective markers." in: PloS one, Vol. 17, Issue 5, pp. e0261743, (2022) (PubMed).

Perisic, Hedin, Razuvaev, Lengquist, Osterholm, Folkersen, Gillgren, Paulsson-Berne, Ponten, Odeberg, Hedin: "Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 33, Issue 10, pp. 2432-43, (2013) (PubMed).

Jin, Wang, Millar, Quertermous, Rothblat, Glick, Rader: "Hepatic proprotein convertases modulate HDL metabolism." in: Cell metabolism, Vol. 6, Issue 2, pp. 129-36, (2007) (PubMed).

Klee, Finlay, McDonald, Attewell, Hebrink, Dyer, Love, Vasmatzis, Li, Beechem, Klee: "Bioinformatics methods for prioritizing serum biomarker candidates." in: Clinical chemistry, Vol. 52, Issue 11, pp. 2162-4, (2007) (PubMed).

Khatib, Siegfried, Chrétien, Metrakos, Seidah: "Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy." in: The American journal of pathology, Vol. 160, Issue 6, pp. 1921-35, (2002) (PubMed).

Synonyms and alternative names related to PCSK6

proprotein convertase subtilisin/kexin type 6 (PCSK6), peptidase S8 (EAMY_RS27925), proprotein convertase subtilisin/kexin type 6 (pcsk6), proprotein convertase subtilisin/kexin type 6 (Pcsk6), proprotein convertase subtilisin/kexin type 6 L homeolog (pcsk6.L), C86343, PACE4, Pace4, PACE4AIIa, PCSK6, SPC4, Spc4, spc4, Xpace4

Protein level used designations for PCSK6

  • proprotein convertase PACE4
  • proprotein convertase subtilisin/kexin type 6
  • proprotein convertase subtilisin/kexin type 6-like
  • paired basic amino acid cleaving enzyme 4
  • paired basic amino acid cleaving system 4
  • subtilisin-like proprotein convertase 4
  • subtilisin/kexin-like protease PACE4
  • Subtilisin - like endoprotease
  • kexin-like protease PC7A
  • subtilisin-like kinase SPC4
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