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PCSK5 产品

(Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

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Featured PCSK5 Categories

PCSK5 抗体

High quality antibodies with extensive validation data.

PCSK5 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PCSK5 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PCSK5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7435742
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7164820
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN1881639
Quantity 400 μL
Datasheet Datasheet

Recommended PCSK5 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958853
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5658130
Quantity 96 tests
Datasheet Datasheet

Recommended PCSK5 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1314358
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314359
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7397909
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PCSK5 Products

Heng, Dynon, Li, Edgell, Walton, Rombauts, Vollenhoven, Nie: "Development of a high-throughput assay for human proprotein convertase 5/6 for detecting uterine receptivity." in: Analytical biochemistry, Vol. 475, pp. 14-21, (2015) (PubMed).

Harihar, Pounds, Iwakuma, Seidah, Welch: "Furin is the major proprotein convertase required for KISS1-to-Kisspeptin processing." in: PLoS ONE, Vol. 9, Issue 1, pp. e84958, (2014) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Heng, Paule, Hardman, Li, Singh, Rainczuk, Stephens, Nie: "Posttranslational activation of bone morphogenetic protein 2 is mediated by proprotein convertase 6 during decidualization for pregnancy establishment." in: Endocrinology, Vol. 151, Issue 8, pp. 3909-17, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Iatan, Dastani, Do, Weissglas-Volkov, Ruel, Lee, Huertas-Vazquez, Taskinen, Prat, Seidah, Pajukanta, Engert, Genest: "Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels." in: Circulation. Cardiovascular genetics, Vol. 2, Issue 5, pp. 467-75, (2009) (PubMed).

Szumska, Pieles, Essalmani, Bilski, Mesnard, Kaur, Franklyn, El Omari, Jefferis, Bentham, Taylor, Schneider, Arnold, Johnson, Tymowska-Lalanne, Stammers, Clarke, Neubauer, Morris, Brown, Shaw-Smith, Cama, Capra, Ragoussis, Constam, Seidah, Prat, Bhattacha: "VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5." in: Genes & development, Vol. 22, Issue 11, pp. 1465-77, (2008) (PubMed).

Jin, Wang, Millar, Quertermous, Rothblat, Glick, Rader: "Hepatic proprotein convertases modulate HDL metabolism." in: Cell metabolism, Vol. 6, Issue 2, pp. 129-36, (2007) (PubMed).

Synonyms and alternative names related to PCSK5

proprotein convertase subtilisin/kexin type 5 (PCSK5), proprotein convertase subtilisin/kexin type 5 (Pcsk5), proprotein convertase subtilisin/kexin type 5 S homeolog (pcsk5.S), proprotein convertase subtilisin/kexin type 5 (LOC528098), proprotein convertase subtilisin/kexin type 5 (pcsk5), proprotein convertase subtilisin/kexin type 5b (pcsk5b), b2b585Clo, b2b1549Clo, fur2, MGC98915, PC5, Pc5, PC5/6A, PC5A, PC6, pc6, PC6A, PCSK5, pcsk5, SPC6, spc6, spc6A, spc6a, subtilase, zgc:165659

Protein level used designations for PCSK5

  • hPC6
  • prohormone convertase 5
  • proprotein convertase 6
  • protease PC6
  • subtilisin/kexin-like protease PC5
  • proprotein convertase 5
  • proprotein convertase PC5
  • subtilisin-like proprotein convertase 6
  • proprotein convertase subtilisin/kexin type 5
  • proprotein convertase PC6
  • proprotein convertase 6A
  • proprotein convertase 6B
  • proprotein convertase 6C
  • proprotein convertase 6D
  • proprotein convertase 6E
  • proprotein convertase 6F
  • subtilisin-like protease SPC6A
  • pc5.2
  • pcsk5.2
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