PCDHGA1 抗体
(Protocadherin gamma A1 (PCDHGA1))
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008].
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PCDHGA1 抗体
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Synonyms and alternative names related to PCDHGA1
protocadherin gamma subfamily A, 1 (PCDHGA1), protocadherin gamma-C5 (LOC478038), protocadherin gamma subfamily A, 1 (Pcdhga1), PCDH-GAMMA-A1Protein level used designations for PCDHGA1
- protocadherin gamma-A1
- protocadherin gamma a1
- PCDH-gamma-A1
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