PCBP2 抗体
(Poly(rC) Binding Protein 2 (PCBP2))
The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
recommended
PCBP2 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 5F12 unconjugated
recommended
recommended
PCBP2 抗体 by 应用范围
Find PCBP2 抗体 validated for a specific application such as WB, IF, ELISA, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.
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PCBP2 抗体 by 克隆形成能力
Find available monoclonal or polyclonal PCBP2 抗体. Click on a link to go to the corresponding products.
PCBP2 抗体 by 克隆
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PCBP2 抗体 by 标记
Find PCBP2 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular PCBP2 抗体
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Reactivity
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Validations
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Datasheet
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Application
WB, ELISA, IF, IHC (p), RNAi
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Cat. No.
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Quantity
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Application
WB, IHC, IF
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
ABIN518656
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Guinea Pig, Horse, Human, Mouse, Rat
Application
WB, IHC
Validations
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Datasheet
Datasheet
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Application
WB, IHC, IF
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Cat. No.
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Quantity
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Datasheet
Datasheet
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Application
WB, ELISA, IHC, IF, IHC (p), RNAi
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Cat. No.
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Quantity
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Cat. No.
ABIN6264064
Quantity
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Datasheet
Datasheet
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Application
WB, IHC, IHC (p)
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Cat. No.
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Quantity
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Datasheet
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Application
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
ABIN629951
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IF, IC
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Quantity
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Datasheet
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Latest Publications for our PCBP2 抗体
: "Phosphoinositide-3-kinase inhibition elevates ferritin level resulting depletion of labile iron pool and blocking of glioma cell proliferation." in: Biochimica et biophysica acta. General subjects, Vol. 1863, Issue 3, pp. 547-564, (2019) (PubMed).: "Xist Deletional Analysis Reveals an Interdependency between Xist RNA and Polycomb Complexes for Spreading along the Inactive X." in: Molecular cell, Vol. 74, Issue 1, pp. 101-117.e10, (2019) (PubMed).
: "Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos." in: Scientific reports, Vol. 7, Issue 1, pp. 4022, (2018) (PubMed).
: "Interplay between PCBP2 and miRNA modulates ARHGDIA expression and function in glioma migration and invasion." in: Oncotarget, Vol. 7, Issue 15, pp. 19483-98, (2016) (PubMed).
: "Iron Export through the Transporter Ferroportin 1 Is Modulated by the Iron Chaperone PCBP2." in: The Journal of biological chemistry, Vol. 291, Issue 33, pp. 17303-18, (2016) (PubMed).
: "hnRNP L and NF90 interact with hepatitis C virus 5'-terminal untranslated RNA and promote efficient replication." in: Journal of virology, Vol. 88, Issue 13, pp. 7199-209, (2014) (PubMed).
: "Dissecting noncoding and pathogen RNA-protein interactomes." in: RNA (New York, N.Y.), Vol. 21, Issue 1, pp. 135-43, (2014) (PubMed).
: "RNA-binding protein PCBP2 modulates glioma growth by regulating FHL3." in: The Journal of clinical investigation, Vol. 123, Issue 5, pp. 2103-18, (2013) (PubMed).
: "Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules." in: Nucleic acids research, Vol. 40, Issue 16, pp. 8099-110, (2012) (PubMed).
: "Poly(C)-binding protein 2 interacts with sequences required for viral replication in the hepatitis C virus (HCV) 5' untranslated region and directs HCV RNA replication through circularizing the viral ..." in: Journal of virology, Vol. 85, Issue 16, pp. 7954-64, (2011) (PubMed).
Aliases for PCBP2 抗体
poly(rC) binding protein 2 (PCBP2) 抗体poly(rC) binding protein 2 (Pcbp2) 抗体
poly(rC) binding protein 2 (pcbp2) 抗体
poly(rC) binding protein 2 L homeolog (pcbp2.L) 抗体
alphaCP-2 抗体
AW412548 抗体
fb36h02 抗体
hnRNP-E2 抗体
HNRNPE2 抗体
HNRPE2 抗体
Hnrpx 抗体
PCBP2 抗体
PCBP3 抗体
wu:fb36h02 抗体
zgc:55964 抗体
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