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PC 抗体

(Pyruvate Carboxylase (PC))
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008].
PC 抗体  (AA 36-486) PC 抗体  (AA 36-486) PC 抗体 (AA 36-486) (ABIN7441475)

PC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

PC 抗体  (Internal Region) PC 抗体  (Internal Region) PC 抗体 (Internal Region) (ABIN238663)

Verified PC 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

PC 抗体  (AA 357-406) PC 抗体  (AA 357-406) PC 抗体 (AA 357-406) (ABIN2890557)

PC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

PC 抗体 by Grade

Find PC 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PC 抗体 by 适用

Find PC 抗体 for a variety of species such as anti-Human PC, anti-Mouse PC, anti-Rat PC. The species listed below are among those available. Click on a link to go to the corresponding products.

PC 抗体 by 应用范围

Find PC 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

PC 抗体 by 抗体来源

Find PC 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

PC 抗体 by 抗原表位

Find PC 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PC 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PC 抗体. Click on a link to go to the corresponding products.

PC 抗体 by 标记

Find PC 抗体 with a specific conjugate such as Biotin, FITC, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PC 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7441475
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN238663
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN2890557
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Guinea Pig, Horse, Human, Mouse, Pig
Application WB
Validations
  • (1)
Cat. No. ABIN6746621
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN954396
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
Cat. No. ABIN6283378
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IP, IF
Validations
Cat. No. ABIN7118154
Quantity 100 μg
Datasheet Datasheet
Reactivity Chicken, Cow, Human, Monkey, Mouse, Pig, Rat, Sheep, Zebrafish (Danio rerio)
Application WB
Validations
Cat. No. ABIN2582736
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
Cat. No. ABIN3186353
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
Cat. No. ABIN1817260
Quantity 100 μg
Datasheet Datasheet
Reactivity Saccharomyces cerevisiae
Application WB, ELISA
Validations
Cat. No. ABIN2582732
Quantity 100 μg
Datasheet Datasheet
Reactivity Saccharomyces cerevisiae
Application WB, ELISA
Validations
Cat. No. ABIN2582733
Quantity 100 μg
Datasheet Datasheet
Reactivity Saccharomyces cerevisiae
Application WB, ELISA
Validations
Cat. No. ABIN2582734
Quantity 100 μg
Datasheet Datasheet
Reactivity Saccharomyces cerevisiae
Application ELISA
Validations
Cat. No. ABIN1968540
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IHC (p)
Validations
Cat. No. ABIN1810838
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our PC 抗体

Rattanapornsompong, Ngamkham, Chavalit, Jitrapakdee: "Generation of Human Pyruvate Carboxylase Knockout Cell Lines Using Retrovirus Expressing Short Hairpin RNA and CRISPR-Cas9 as Models to Study Its Metabolic Role in Cancer Research." in: Methods in molecular biology (Clifton, N.J.), Vol. 1916, pp. 273-288, (2019) (PubMed).

Toledo, Batista-Gonzalez, Merheb, Aoun, Tarabra, Feng, Sarparanta, Merlo, Botrè, Schwartz, Pessin, Singh: "Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1." in: Cell metabolism, Vol. 28, Issue 2, pp. 268-281.e4, (2018) (PubMed).

Cardaci, Zheng, MacKay, van den Broek, MacKenzie, Nixon, Stevenson, Tumanov, Bulusu, Kamphorst, Vazquez, Fleming, Schiavi, Kalna, Blyth, Strathdee, Gottlieb: "Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis." in: Nature cell biology, Vol. 17, Issue 10, pp. 1317-26, (2015) (PubMed).

Seale, Gilman, Hashimoto, Ogawa-Wong, Berry: "Diet-induced obesity in the selenocysteine lyase knockout mouse." in: Antioxidants & redox signaling, Vol. 23, Issue 10, pp. 761-74, (2015) (PubMed).

Lee, Jung, Choi, Lee, Lee, Han, Kim, Kim, Lee, Kang: "Toxicity generated through inhibition of pyruvate carboxylase and carnitine palmitoyl transferase-1 is similar to high glucose/palmitate-induced glucolipotoxicity in INS-1 beta cells." in: Molecular and cellular endocrinology, Vol. 383, Issue 1-2, pp. 48-59, (2014) (PubMed).

Tao, Zhang, Zeng, Shulman, Jin: "Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice." in: Nature medicine, Vol. 20, Issue 11, pp. 1263-9, (2014) (PubMed).

Lee, Reyes, Gottipati, Lewis, Lesort, Parpura, Gray: "Enhanced Ca(2+)-dependent glutamate release from astrocytes of the BACHD Huntington's disease mouse model." in: Neurobiology of disease, Vol. 58, pp. 192-9, (2013) (PubMed).

Vastag, Koyuncu, Grady, Shenk, Rabinowitz: "Divergent effects of human cytomegalovirus and herpes simplex virus-1 on cellular metabolism." in: PLoS pathogens, Vol. 7, Issue 7, pp. e1002124, (2011) (PubMed).

St Maurice, Reinhardt, Surinya, Attwood, Wallace, Cleland, Rayment: "Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme." in: Science (New York, N.Y.), Vol. 317, Issue 5841, pp. 1076-9, (2007) (PubMed).

Li, Han, Li, Kan, Fan, Li, Ji, Zhao, Zhang, Grigalavicius, Berge, Goscinski, Nesland, Suo: "Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells." in: Oncotarget, Vol. 8, Issue 28, pp. 46363-46380 (PubMed).

Aliases for PC 抗体

Pyruvate carboxylase (PCB) 抗体
pyruvate carboxylase b (pcxb) 抗体
PYruvate Carboxylase (pyc-1) 抗体
pyruvate carboxylase (PC) 抗体
pyruvate carboxylase (pyc) 抗体
pyruvate carboxylase Pyr1 (pyr1) 抗体
pyruvate carboxylase (CNF00650) 抗体
Pyruvate carboxylase (PYC1) 抗体
pyruvate carboxylase (Ndas_1152) 抗体
pyruvate carboxylase (Ilyop_2503) 抗体
pyruvate carboxylase (Calni_0495) 抗体
pyruvate carboxylase (Ftrac_1004) 抗体
pyruvate carboxylase (Plabr_3574) 抗体
pyruvate carboxylase (Sgly_2936) 抗体
pyruvate carboxylase (Celly_0558) 抗体
pyruvate carboxylase (Hipma_0131) 抗体
pyruvate carboxylase (Halhy_1567) 抗体
pyruvate carboxylase (Mesop_1269) 抗体
pyruvate carboxylase (Pcx) 抗体
pyruvate carboxylase (Pc) 抗体
BA4157 抗体
BcDNA 抗体
BcDNA:GH06348 抗体
Dmel\\CG1516 抗体
PC 抗体
Pc 抗体
Pcb 抗体
PCB 抗体
PCX 抗体
Pcx 抗体
pyc 抗体
wu:fb82g08 抗体
wu:fj85g01 抗体
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