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PBX1 抗体

(Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1\;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].
PBX1 抗体  (AA 213-321) PBX1 抗体  (AA 213-321) PBX1 抗体 (AA 213-321) (ABIN562114)

PBX1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4A2 unconjugated

PBX1 抗体  (AA 315-430) PBX1 抗体  (AA 315-430) PBX1 抗体 (AA 315-430) (ABIN7164137)

PBX1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated

PBX1 抗体  (Internal Region) PBX1 抗体  (Internal Region) PBX1 抗体 (Internal Region) (ABIN571168)

Verified PBX1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

PBX1 抗体 by Grade

Find PBX1 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PBX1 抗体 by 适用

Find PBX1 抗体 for a variety of species such as anti-Human PBX1, anti-Mouse PBX1, anti-Rat PBX1. The species listed below are among those available. Click on a link to go to the corresponding products.

PBX1 抗体 by 应用范围

Find PBX1 抗体 validated for a specific application such as WB, ELISA, IF, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PBX1 抗体 by 抗体来源

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PBX1 抗体 by 抗原表位

Find PBX1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PBX1 抗体 by 克隆形成能力

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PBX1 抗体 by 克隆

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PBX1 抗体 by 标记

Find PBX1 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PBX1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (5)
  • (5)
Cat. No. ABIN562114
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC
Validations
  • (3)
Cat. No. ABIN7164137
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN571168
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN562113
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN518648
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human, Monkey, Mouse, Pig, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6736594
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6145269
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, ICC
Validations
  • (1)
Cat. No. ABIN2856072
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Mouse, Pig, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN2777186
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validations
Cat. No. ABIN1714066
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7164140
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7164139
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7164138
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, IP
Validations
Cat. No. ABIN7117746
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
Cat. No. ABIN6760400
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PBX1 抗体

DellOrso, Wang, Shih, Saso, Berghella, Gutierrez-Cruz, Ladurner, OShea, Sartorelli, Zare: "The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1." in: Cell reports, Vol. 14, Issue 5, pp. 1156-1168, (2016) (PubMed).

Nguyen, Barozzi, Faronato, Lombardo, Steel, Patel, Darbre, Castellano, Győrffy, Woodley, Meira, Patten, Vircillo, Periyasamy, Ali, Frige, Minucci, Coombes, Magnani: "Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion." in: Nature communications, Vol. 6, pp. 10044, (2015) (PubMed).

Petrini, Wang, Zucali, Lee, Pham, Voeller, Meltzer, Giaccone: "Copy number aberrations of genes regulating normal thymus development in thymic epithelial tumors." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 8, pp. 1960-71, (2013) (PubMed).

Bjerke, Hyman-Walsh, Wotton: "Cooperative transcriptional activation by Klf4, Meis2, and Pbx1." in: Molecular and cellular biology, Vol. 31, Issue 18, pp. 3723-33, (2011) (PubMed).

Magnani, Ballantyne, Zhang, Lupien: "PBX1 genomic pioneer function drives ER? signaling underlying progression in breast cancer." in: PLoS genetics, Vol. 7, Issue 11, pp. e1002368, (2011) (PubMed).

Cheung, Chan, Chan, Ikegawa, Kou, Ngai, Smith, Luk, Huang, Mori, Sham, Kung: "Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation." in: Human molecular genetics, Vol. 18, Issue 4, pp. 679-87, (2009) (PubMed).

Horman, Velu, Chaubey, Bourdeau, Zhu, Paul, Gebelein, Grimes: "Gfi1 integrates progenitor versus granulocytic transcriptional programming." in: Blood, Vol. 113, Issue 22, pp. 5466-75, (2009) (PubMed).

Duesing, Charpentier, Marre, Tichet, Hercberg, Balkau, Froguel, Gibson: "Evaluating the association of common PBX1 variants with type 2 diabetes." in: BMC medical genetics, Vol. 9, pp. 14, (2008) (PubMed).

Park, Shih, Wang: "Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer." in: Cancer research, Vol. 68, Issue 21, pp. 8852-60, (2008) (PubMed).

Qiu, Tomita, Zhang, Nakamichi, Morii, Aozasa: "Pre-B-cell leukemia transcription factor 1 regulates expression of valosin-containing protein, a gene involved in cancer growth." in: The American journal of pathology, Vol. 170, Issue 1, pp. 152-9, (2007) (PubMed).

Aliases for PBX1 抗体

PBX homeobox 1 (PBX1) 抗体
pre-B-cell leukemia homeobox 1a (pbx1a) 抗体
pre B cell leukemia homeobox 1 (Pbx1) 抗体
PBX homeobox 1 (Pbx1) 抗体
pre-B-cell leukemia homeobox 1 S homeolog (pbx1.S) 抗体
2310056B04Rik 抗体
AI848790 抗体
AU015730 抗体
D230003C07Rik 抗体
fi29e01 抗体
Pbx-1 抗体
Pbx1a 抗体
PBX1A 抗体
pbx1b 抗体
Pbx1b 抗体
wu:fi29e01 抗体
Xpbx1 抗体
Xpbx1b 抗体
zgc:55265 抗体
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