P4HTM 产品
(Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
Categories
The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Featured P4HTM Categories
Recommended P4HTM 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Bat, Cow, Dog, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6744213
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6741725
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN527161
Quantity
100 μg
Datasheet
Datasheet
Recommended P4HTM 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313840
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3118601
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3124637
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our P4HTM Products
: "PHD4 stimulates tumor angiogenesis in osteosarcoma cells via TGF-α." in: Molecular cancer research : MCR, Vol. 11, Issue 11, pp. 1337-48, (2013) (PubMed).: "Prolyl hydroxylases 2 and 3 act in gliomas as protective negative feedback regulators of hypoxia-inducible factors." in: Cancer research, Vol. 70, Issue 1, pp. 357-66, (2010) (PubMed).
: "Peroxisomal localization of hypoxia-inducible factors and hypoxia-inducible factor regulatory hydroxylases in primary rat hepatocytes exposed to hypoxia-reoxygenation." in: The American journal of pathology, Vol. 169, Issue 4, pp. 1251-69, (2006) (PubMed).
: "Oxygen sensors and angiogenesis." in: Seminars in cell & developmental biology, Vol. 13, Issue 1, pp. 29-37, (2002) (PubMed).
: "Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 21, pp. 13459-64, (2002) (PubMed).
: "A conserved family of prolyl-4-hydroxylases that modify HIF." in: Science (New York, N.Y.), Vol. 294, Issue 5545, pp. 1337-40, (2001) (PubMed).
Synonyms and alternative names related to P4HTM
prolyl 4-hydroxylase, transmembrane (P4htm), prolyl 4-hydroxylase, transmembrane (P4HTM), prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), shisa family member 5 (SHISA5), 4933406E20Rik, AI853847, BB128974, EGLN4, HIFPH4, P4H-TM, Ph-4, PH-4, PH4, PHD4, RGD1311848Protein level used designations for P4HTM
- hypoxia-inducible factor prolyl 4-hydroxylase
- transmembrane prolyl 4-hydroxylase
- HIF-PH4
- HIF-prolyl hydroxylase 4
- HPH-4
- P4H with transmembrane domain
- Prolyl hydroxlase domain-containing 4
- hypoxia inducible factor prolyl 4 hydroxylase
- hypoxia-inducible factor prolyl hydroxylase 4
- proline 4-hydroxylase
- P4H-TM
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