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p21 蛋白

(Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Nov 2010].

recommended

p21 Protein (AA 2-164) (His-IF2DI Tag) (ABIN7122535)

CDKN1A 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

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recommended

p21 Protein (AA 65-164) (GST tag) (ABIN1349007)

CDKN1A 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

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recommended

p21 Protein (AA 1-164) (GST tag) (ABIN1349005)

CDKN1A 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

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p21 蛋白 by Origin

Find p21 蛋白 for a variety of species such as anti-Human p21, anti-Mouse p21, anti-Cat p21. The species listed below are among those available. Click on a link to go to the corresponding products.

p21 蛋白 by Source

Here you will find p21 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

p21 蛋白 by 蛋白类型

Here you can find p21 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

p21 蛋白 by 应用范围

Find p21 蛋白 validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular p21 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

p21 Protein (AA 2-164) (His-IF2DI Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7122535

Quantity 50 μg

Datasheet Datasheet

p21 Protein (AA 65-164) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1349007

Quantity 10 μg

Datasheet Datasheet

p21 Protein (AA 1-164) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1349005

Quantity 10 μg

Datasheet Datasheet

p21 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2713874

Quantity 20 μg

Datasheet Datasheet

p21 Protein (AA 40-164) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7505149

Quantity 100 μg

Datasheet Datasheet

p21 Protein (AA 1-164) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7404383

Quantity 100 μg

Datasheet Datasheet

p21 Protein (AA 2-159) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7398071

Quantity 100 μg

Datasheet Datasheet

p21 Protein (AA 1-164) (His tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7398074

Quantity 100 μg

Datasheet Datasheet

p21 Protein (AA 2-164) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1097281

Quantity 50 μg

Datasheet Datasheet

p21 蛋白

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2128477

Quantity 20 μg

Datasheet Datasheet

p21 Protein (AA 2-164) (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN5709265

Quantity 100 μg

Datasheet Datasheet

p21 Protein (AA 425-719, partial) (His-SUMO Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN5711920

Quantity 100 μg

Datasheet Datasheet

p21 Protein (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6699762

Quantity 50 μg

Datasheet Datasheet

p21 蛋白

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6120577

Quantity 100 μg

Datasheet Datasheet

p21 Protein (AA 2-164) (His tag)

Reactivity Cat

Source Yeast

Validations

Cat. No. ABIN1458670

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our p21 蛋白

Porter, Farmaki, Altilia, Schools, West, Chen, Chang, Puzyrev, Lim, Rokow-Kittell, Friedhoff, Papavassiliou, Kalurupalle, Hurteau, Shi, Baran, Gyorffy, Wentland, Broude, Kiaris, Roninson: "Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 34, pp. 13799-804, (2012) (PubMed).

Aliases for p21 蛋白

cyclin D1 (CCND1) 蛋白
cyclin dependent kinase inhibitor 1A (CDKN1A) 蛋白
cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a) 蛋白
cyclin-dependent kinase inhibitor 1A (Cdkn1a) 蛋白
cyclin-dependent kinase inhibitor 1A L homeolog (cdkn1a.L) 蛋白
cyclin-dependent kinase inhibitor 1 (cki1) 蛋白
cyclin-dependent kinase inhibitor 1A (cdkn1a) 蛋白
cyclin dependent kinase inhibitor 1A (Cdkn1a) 蛋白
KRAS proto-oncogene, GTPase (KRAS) 蛋白
CAP20 蛋白
cap20 蛋白
CCND1 蛋白
CDKI 蛋白
CDKN1 蛋白
Cdkn1 蛋白
cdkn1 蛋白
CDKN1A 蛋白
CIP1 蛋白
Cip1 蛋白
cip1 蛋白
KRAS2 蛋白
MDA-6 蛋白
mda-6 蛋白
mda6 蛋白
p16Xic2 蛋白
P21 蛋白
p21 蛋白
p21CIP1 蛋白
p21Cip1 蛋白
p21cip1 蛋白
p21ras 蛋白
p21WAF 蛋白
SDI1 蛋白
sdi1 蛋白
si:ch1073-48m5.2 蛋白
UV96 蛋白
WAF1 蛋白
Waf1 蛋白
waf1 蛋白

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p21 蛋白 by Origin

p21 蛋白 by Source

p21 蛋白 by 蛋白类型

p21 蛋白 by 应用范围

Popular p21 蛋白

Latest Publications for our p21 蛋白

Aliases for p21 蛋白

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