p107 抗体
(Retinoblastoma-Like 1 (p107) (RBL1))
The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Popular p107 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, PLA
Validations
- (3)
Cat. No.
ABIN562602
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
- (1)
Cat. No.
ABIN1881732
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN1327455
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN6263929
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN389640
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
Cat. No.
ABIN713381
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7167787
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Horse, Human, Mouse, Pig
Application
WB
Validations
- (1)
Cat. No.
ABIN6744383
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Horse, Human, Monkey, Mouse, Pig, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6742280
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7269942
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (2)
Cat. No.
ABIN2792553
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN358209
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN755068
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN760691
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN755070
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our p107 抗体
: "XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies." in: Oncotarget, Vol. 9, Issue 77, pp. 34567-34581, (2018) (PubMed).: "The 140-kD isoform of CD56 (NCAM1) directs the molecular pathogenesis of ischemic cardiomyopathy." in: The American journal of pathology, Vol. 182, Issue 4, pp. 1205-18, (2013) (PubMed).
: "B55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activation." in: The Journal of biological chemistry, Vol. 285, Issue 39, pp. 29863-73, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
: "Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis." in: British journal of cancer, Vol. 101, Issue 8, pp. 1461-8, (2009) (PubMed).
: "p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2." in: The Journal of cell biology, Vol. 168, Issue 1, pp. 55-66, (2005) (PubMed).
: "The cell cycle-regulated B-Myb transcription factor overcomes cyclin-dependent kinase inhibitory activity of p57(KIP2) by interacting with its cyclin-binding domain." in: The Journal of biological chemistry, Vol. 278, Issue 45, pp. 44255-64, (2003) (PubMed).
: "Mullerian Inhibiting Substance inhibits cervical cancer cell growth via a pathway involving p130 and p107." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 26, pp. 15601-6, (2003) (PubMed).
: "Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300." in: Genes & development, Vol. 9, Issue 10, pp. 1188-98, (1995) (PubMed).
: "In vivo association of E2F and DP family proteins." in: Molecular and cellular biology, Vol. 15, Issue 5, pp. 2536-46, (1995) (PubMed).
Aliases for p107 抗体
retinoblastoma-like 1 L homeolog (rbl1.L) 抗体RB transcriptional corepressor like 1 (RBL1) 抗体
retinoblastoma-like 1 (p107) (rbl1) 抗体
retinoblastoma-like 1 (rbl1) 抗体
retinoblastoma-like 1 (p107) (RBL1) 抗体
RB transcriptional corepressor like 1 (rbl1) 抗体
retinoblastoma-like 1 (p107) (Rbl1) 抗体
RB transcriptional corepressor like 1 (Rbl1) 抗体
AW547426 抗体
CP107 抗体
fj58e06 抗体
p107 抗体
prb1 抗体
PRB1 抗体
wu:fj58e06 抗体
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