电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

p107 产品

(Retinoblastoma-Like 1 (p107) (RBL1))
The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured p107 Categories

p107 抗体

High quality antibodies with extensive validation data.

p107 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

p107 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended p107 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (3)
Cat. No. ABIN562602
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN1881732
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN1327455
Quantity 50 μg
Datasheet Datasheet

Recommended p107 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969920
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1155324
Quantity 96 tests
Datasheet Datasheet

Recommended p107 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317569
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094884
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3135610
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our p107 Products

Baek, Lombard, Libertini, Fernandez-Rubio, Vinall, Gandour-Edwards, Nakagawa, Vidallo, Nishida, Siddiqui, Wettersten, Landesman, Weiss, Ghosh, Mudryj: "XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies." in: Oncotarget, Vol. 9, Issue 77, pp. 34567-34581, (2018) (PubMed).

Flowers, Patel, Gleicher, Amer, Himelman, Goel, Moran: "p107-Dependent recruitment of SWI/SNF to the alkaline phosphatase promoter during osteoblast differentiation." in: Bone, Vol. 69, pp. 47-54, (2014) (PubMed).

Tur, Etschmann, Benz, Leich, Waller, Schuh, Rosenwald, Ertl, Kienitz, Haaf, Bräuninger, Gattenlöhner: "The 140-kD isoform of CD56 (NCAM1) directs the molecular pathogenesis of ischemic cardiomyopathy." in: The American journal of pathology, Vol. 182, Issue 4, pp. 1205-18, (2013) (PubMed).

Jayadeva, Kurimchak, Garriga, Sotillo, Davis, Haines, Mumby, Graña: "B55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activation." in: The Journal of biological chemistry, Vol. 285, Issue 39, pp. 29863-73, (2010) (PubMed).

Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

Cunningham, Vierkant, Sellers, Phelan, Rider, Liebow, Schildkraut, Berchuck, Couch, Wang, Fridley, Gentry-Maharaj, Menon, Hogdall, Kjaer, Whittemore, DiCioccio, Song, Gayther, Ramus, Pharaoh, Goode: "Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis." in: British journal of cancer, Vol. 101, Issue 8, pp. 1461-8, (2009) (PubMed).

Rodier, Makris, Coulombe, Scime, Nakayama, Nakayama, Meloche: "p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2." in: The Journal of cell biology, Vol. 168, Issue 1, pp. 55-66, (2005) (PubMed).

Joaquin, Watson: "The cell cycle-regulated B-Myb transcription factor overcomes cyclin-dependent kinase inhibitory activity of p57(KIP2) by interacting with its cyclin-binding domain." in: The Journal of biological chemistry, Vol. 278, Issue 45, pp. 44255-64, (2003) (PubMed).

Barbie, Barbie, MacLaughlin, Maheswaran, Donahoe: "Mullerian Inhibiting Substance inhibits cervical cancer cell growth via a pathway involving p130 and p107." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 26, pp. 15601-6, (2003) (PubMed).

Lee, Galvin, See, Eckner, Livingston, Moran, Shi: "Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300." in: Genes & development, Vol. 9, Issue 10, pp. 1188-98, (1995) (PubMed).

Synonyms and alternative names related to p107

retinoblastoma-like 1 L homeolog (rbl1.L), RB transcriptional corepressor like 1 (RBL1), retinoblastoma-like 1 (p107) (rbl1), retinoblastoma-like 1 (rbl1), retinoblastoma-like 1 (p107) (RBL1), RB transcriptional corepressor like 1 (rbl1), retinoblastoma-like 1 (p107) (Rbl1), RB transcriptional corepressor like 1 (Rbl1), AW547426, CP107, fj58e06, p107, prb1, PRB1, wu:fj58e06

Protein level used designations for p107

  • retinoblastoma-like 1 (p107)
  • retinoblastoma-like protein 1
  • retinoblastoma-like protein 1-like
  • 107 kDa retinoblastoma-associated protein
  • cellular protein 107
You are here:
客服