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PARL 抗体

(Presenilin Associated, Rhomboid-Like (PARL))
This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
PARL 抗体  (N-Term) PARL 抗体  (N-Term) PARL 抗体 (N-Term) (ABIN2782038)

PARL 适用: 人, 小鼠, 大鼠, 犬, Pig, 兔, 马, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

PARL 抗体  (N-Term) PARL 抗体  (N-Term) PARL 抗体 (N-Term) (ABIN634971)

PARL 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

PARL 抗体  (AA 1-170) PARL 抗体  (AA 1-170) PARL 抗体 (AA 1-170) (ABIN7164273)

PARL 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

PARL 抗体 by 适用

Find PARL 抗体 for a variety of species such as anti-Human PARL, anti-Mouse PARL, anti-Rat PARL. The species listed below are among those available. Click on a link to go to the corresponding products.

PARL 抗体 by 应用范围

Find PARL 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PARL 抗体 by 抗体来源

Find PARL 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

PARL 抗体 by 抗原表位

Find PARL 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PARL 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PARL 抗体. Click on a link to go to the corresponding products.

PARL 抗体 by 克隆

Find PARL 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

PARL 抗体 by 标记

Find PARL 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PARL 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB, IHC
Validations
  • (1)
  • (5)
Cat. No. ABIN2782038
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Mouse, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN634971
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7164273
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Dog, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6738135
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN969340
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7164272
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (1)
Cat. No. ABIN527539
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, EIA
Validations
  • (2)
Cat. No. ABIN500451
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
Cat. No. ABIN6990962
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Chicken, Human, Mouse, Primate, Rat
Application WB, ELISA, IHC, FM
Validations
Cat. No. ABIN1607894
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (1)
Cat. No. ABIN1737869
Quantity 50 μg
Datasheet Datasheet
Reactivity Dog, Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN2463992
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN6864669
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN6840479
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN6824416
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PARL 抗体

Yoshioka, Katsu, Sakata, Okami, Wakai, Kinouchi, Chan: "The role of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 11, pp. 1658-65, (2013) (PubMed).

Chao, Parganas, Boyd, Hong, Opferman, Ihle: "Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons." in: Nature, Vol. 452, Issue 7183, pp. 98-102, (2008) (PubMed).

Cipolat, Rudka, Hartmann, Costa, Serneels, Craessaerts, Metzger, Frezza, Annaert, DAdamio, Derks, Dejaegere, Pellegrini, DHooge, Scorrano, De Strooper: "Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling." in: Cell, Vol. 126, Issue 1, pp. 163-75, (2006) (PubMed).

Jeyaraju, Xu, Letellier, Bandaru, Zunino, Berg, McBride, Pellegrini: "Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 49, pp. 18562-7, (2006) (PubMed).

McQuibban, Saurya, Freeman: "Mitochondrial membrane remodelling regulated by a conserved rhomboid protease." in: Nature, Vol. 423, Issue 6939, pp. 537-41, (2003) (PubMed).

Pellegrini, Passer, Canelles, Lefterov, Ganjei, Fowlkes, Koonin, DAdamio: "PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2." in: Journal of Alzheimer's disease : JAD, Vol. 3, Issue 2, pp. 181-190, (2002) (PubMed).

Aliases for PARL 抗体

presenilin associated rhomboid like (PARL) 抗体
presenilin associated, rhomboid-like (Parl) 抗体
presenilin associated rhomboid like (Parl) 抗体
presenilin associated, rhomboid-like a (parla) 抗体
D16Ertd607e 抗体
parl 抗体
PRO2207 抗体
PSARL 抗体
Psarl 抗体
PSARL1 抗体
PSENIP2 抗体
RHBDS1 抗体
zgc:112986 抗体
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