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Parkin 抗体

(Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
The precise function of this gene is unknown\; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008].
Parkin 抗体  (AA 288-387) Parkin 抗体  (AA 288-387) Parkin 抗体 (AA 288-387) (ABIN562106)

PARK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1H4 unconjugated

Parkin 抗体  (AA 1-300) Parkin 抗体  (AA 1-300) Parkin 抗体 (AA 1-300) (ABIN3021179)

PARK2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

Parkin 抗体  (C-Term) Parkin 抗体  (C-Term) Parkin 抗体 (C-Term) (ABIN390366)

PARK2 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB07373 unconjugated

Parkin 抗体 by 适用

Find Parkin 抗体 for a variety of species such as anti-Human Parkin, anti-Rat Parkin, anti-Mouse Parkin. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find Parkin 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

Parkin 抗体 by 抗体来源

Find Parkin 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

Parkin 抗体 by 抗原表位

Find Parkin 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Parkin 抗体 by 克隆形成能力

Find available monoclonal or polyclonal Parkin 抗体. Click on a link to go to the corresponding products.

Parkin 抗体 by 克隆

Find Parkin 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

Parkin 抗体 by 标记

Find Parkin 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Parkin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN562106
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (10)
Cat. No. ABIN3021179
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, FACS, IHC (p)
Validations
  • (6)
Cat. No. ABIN390366
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, FACS
Validations
  • (6)
Cat. No. ABIN3032153
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, FACS
Validations
  • (7)
Cat. No. ABIN3032156
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Rat
Application WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro)
Validations
  • (1)
  • (3)
Cat. No. ABIN735578
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7151093
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
Cat. No. ABIN7193428
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), ICC
Validations
  • (5)
Cat. No. ABIN3043896
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, FACS
Validations
  • (3)
Cat. No. ABIN1574065
Quantity 40 μg
Datasheet Datasheet
Reactivity Human
Application WB, PLA
Validations
  • (2)
Cat. No. ABIN518619
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN518618
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6747194
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN361515
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN711251
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Parkin 抗体

Lin, Li, Jiang, Shao, Zhang, Jin, Zhang, Shen, Zhou, Zhou, Gu, Lu, Ni: "PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation." in: Redox biology, Vol. 26, pp. 101254, (2019) (PubMed).

Eid, Ito, Otsuki: "Triggering of Parkin Mitochondrial Translocation in Mitophagy: Implications for Liver Diseases." in: Frontiers in pharmacology, Vol. 7, pp. 100, (2016) (PubMed).

Ma, Zhu, Gao, Rebecchi, Wang, Liu: "Restoring Pharmacologic Preconditioning in the Aging Heart: Role of Mitophagy/Autophagy." in: The journals of gerontology. Series A, Biological sciences and medical sciences, (2016) (PubMed).

Eid, Ito, Horibe, Otsuki: "Ethanol-induced mitophagy in liver is associated with activation of the PINK1-Parkin pathway triggered by oxidative DNA damage." in: Histology and histopathology, Vol. 31, Issue 10, pp. 1143-59, (2016) (PubMed).

Maugeri, DAmico, Reitano, Saccone, Federico, Cavallaro, DAgata: "Parkin modulates expression of HIF-1α and HIF-3α during hypoxia in gliobastoma-derived cell lines in vitro." in: Cell and tissue research, Vol. 364, Issue 3, pp. 465-74, (2016) (PubMed).

Qi, Qiu, Gu, Tian, Zhang: "ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts." in: Scientific reports, Vol. 6, pp. 24700, (2016) (PubMed).

DAmico, Maugeri, Magro, Salvatorelli, Drago, DAgata: "Expression pattern of parkin isoforms in lung adenocarcinomas." in: Tumour biology, (2015) (PubMed).

Li, Zhang, Wang, Liu, Yang, Liu, Lu: "Neuroprotective effects of extract of Acanthopanax senticosus harms on SH-SY5Y cells overexpressing wild-type or A53T mutant ?-synuclein." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 21, Issue 5, pp. 704-11, (2014) (PubMed).

Scuderi, La Cognata, Drago, Cavallaro, DAgata: "Alternative splicing generates different parkin protein isoforms: evidences in human, rat, and mouse brain." in: BioMed research international, Vol. 2014, pp. 690796, (2014) (PubMed).

La Cognata, Iemmolo, DAgata, Scuderi, Drago, Zappia, Cavallaro: "Increasing the Coding Potential of Genomes Through Alternative Splicing: The Case of PARK2 Gene." in: Current genomics, Vol. 15, Issue 3, pp. 203-16, (2014) (PubMed).

Aliases for Parkin 抗体

parkin (park) 抗体
parkin RBR E3 ubiquitin protein ligase (PRKN) 抗体
parkin RBR E3 ubiquitin protein ligase (Prkn) 抗体
parkin RBR E3 ubiquitin protein ligase (prkn) 抗体
parkin (CpipJ_CPIJ014867) 抗体
Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) 抗体
AR-JP 抗体
CG10523 抗体
Dmel\\CG10523 抗体
Dpark 抗体
dpk 抗体
LPRS2 抗体
Park 抗体
PARK2 抗体
PDJ 抗体
pdr-1 抗体
PRKN 抗体
Prkn 抗体
SD01679 抗体
si:ch211-123f21.1 抗体
zgc:112390 抗体
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