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PAPPA 产品

(Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. [provided by RefSeq, Jul 2008].

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Featured PAPPA Categories

PAPPA 抗体

High quality antibodies with extensive validation data.

PAPPA ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PAPPA 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PAPPA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, StM
Validations
  • (4)
Cat. No. ABIN6940248
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN718931
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC
Validations
  • (3)
Cat. No. ABIN7477551
Quantity 1 mL
Datasheet Datasheet

Recommended PAPPA ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969481
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958710
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958711
Quantity 96 tests
Datasheet Datasheet

Recommended PAPPA 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313974
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7411327
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7392137
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PAPPA Products

Pan, Hanada, Zhao, Mao, Ma: "Protein secretion is required for pregnancy-associated plasma protein-A to promote lung cancer growth in vivo." in: PLoS ONE, Vol. 7, Issue 11, pp. e48799, (2012) (PubMed).

Qin, Christiansen, Pettersson: "Point-of-care time-resolved immunofluorometric assay for human pregnancy-associated plasma protein A: use in first-trimester screening for Down syndrome." in: Clinical chemistry, Vol. 48, Issue 3, pp. 473-83, (2002) (PubMed).

Synonyms and alternative names related to PAPPA

pappalysin 1 (PAPPA), pregnancy-associated plasma protein A (Pappa), pappalysin 1 (Pappa1), pappalysin 1 (Pappa), 8430414N03Rik, ASBABP2, DIPLA1, IGFBP-4ase, PAG1, PAPA, PAPP-A, Pappa, PAPPA1

Protein level used designations for PAPPA

  • IGF-dependent IGFBP-4 protease
  • insulin-like growth factor-dependent IGF-binding protein 4 protease
  • pappalysin-1
  • aspecific BCL2 ARE-binding protein 2
  • differentially placenta 1 expressed protein
  • insulin-like growth factor-dependent IGF binding protein-4 protease
  • pregnacy-associated plasma protein A
  • PAPPA-like protein
  • pregnancy-associated plasma protein A-like protein
  • cleaves insulin-like binding protein-4 (IGFBP-4)
  • metalloprotease
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