PAK7 产品
(P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
Categories
The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].
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Featured PAK7 Categories
Recommended PAK7 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ELISA
Validations
- (5)
Cat. No.
ABIN3028909
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN392438
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN671496
Quantity
100 μL
Datasheet
Datasheet
Recommended PAK7 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509061
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094438
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136334
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PAK7 Products
: "p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD." in: Molecular and cellular biology, Vol. 23, Issue 16, pp. 5526-39, (2003) (PubMed).: "p21-activated kinases: three more join the Pak." in: The international journal of biochemistry & cell biology, Vol. 34, Issue 7, pp. 713-7, (2002) (PubMed).
: "Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain." in: Oncogene, Vol. 21, Issue 24, pp. 3939-48, (2002) (PubMed).
: "PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells." in: Molecular and cellular biology, Vol. 22, Issue 2, pp. 567-77, (2001) (PubMed).
Synonyms and alternative names related to PAK7
p21 (RAC1) activated kinase 5 (PAK5), p21 (RAC1) activated kinase 5 L homeolog (pak5.L), p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7), p21 (RAC1) activated kinase 7 (Pak7), 2900083L08Rik, 6430627N20, PAK-5, PAK-7, PAK5, pak5, Pak5Protein level used designations for PAK7
- PAK-5
- PAK-7
- p21(CDKN1A)-activated kinase 7
- p21-activated kinase 5
- p21-activated kinase 7
- p21CDKN1A-activated kinase 7
- protein kinase PAK5
- serine/threonine-protein kinase PAK 7
- serine/threonine-protein kinase PAK7
- p21 (CDKN1A)-activated kinase 7
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