PAK6 抗体
(P21-Activated Kinase 6 (PAK6))
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013].
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PAK6 抗体 by 应用范围
Find PAK6 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
PAK6 抗体 by 抗体来源
Find PAK6 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
PAK6 抗体 by 克隆形成能力
Find available monoclonal or polyclonal PAK6 抗体. Click on a link to go to the corresponding products.
PAK6 抗体 by 克隆
Find PAK6 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular PAK6 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (5)
Cat. No.
ABIN3032120
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN528014
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF
Validations
- (4)
Cat. No.
ABIN656098
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7169136
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Horse, Human, Monkey
Application
IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN1049227
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Horse, Human, Monkey, Mouse, Rabbit, Rat
Application
ELISA, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN213527
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN6145190
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN3032121
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, EIA
Validations
- (3)
Cat. No.
ABIN953980
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (1)
Cat. No.
ABIN7263839
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN3044285
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN3032122
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN500445
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, EIA
Validations
- (1)
- (1)
Cat. No.
ABIN360326
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Mouse
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN754618
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our PAK6 抗体
: "Pyruvate kinase M2 promotes pancreatic ductal adenocarcinoma invasion and metastasis through phosphorylation and stabilization of PAK2 protein." in: Oncogene, Vol. 37, Issue 13, pp. 1730-1742, (2019) (PubMed).: "Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells." in: Oncotarget, Vol. 7, Issue 38, pp. 61229-61245, (2016) (PubMed).
: "Diversity of antigen-specific responses induced in vivo with CTLA-4 blockade in prostate cancer patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 7, pp. 3759-66, (2012) (PubMed).
: "Activation of p21-activated kinase 6 by MAP kinase kinase 6 and p38 MAP kinase." in: The Journal of biological chemistry, Vol. 280, Issue 5, pp. 3323-30, (2005) (PubMed).
: "Mechanism of p21-activated kinase 6-mediated inhibition of androgen receptor signaling." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1922-31, (2004) (PubMed).
: "Identification of an autoinhibitory domain of p21-activated protein kinase 5." in: The Journal of biological chemistry, Vol. 278, Issue 36, pp. 33621-4, (2003) (PubMed).
: "p21-activated kinases: three more join the Pak." in: The international journal of biochemistry & cell biology, Vol. 34, Issue 7, pp. 713-7, (2002) (PubMed).
: "AR and ER interaction with a p21-activated kinase (PAK6)." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 1, pp. 85-99, (2002) (PubMed).
: "Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain." in: Oncogene, Vol. 21, Issue 24, pp. 3939-48, (2002) (PubMed).
: "Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6." in: The Journal of biological chemistry, Vol. 276, Issue 18, pp. 15345-53, (2001) (PubMed).
Aliases for PAK6 抗体
p21 (RAC1) activated kinase 6 (PAK6) 抗体p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6) 抗体
p21 (RAC1) activated kinase 6 (Pak6) 抗体
p21 protein (Cdc42/Rac)-activated kinase 6b (pak6b) 抗体
p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6) 抗体
4732456M09 抗体
PAK5 抗体
pak6 抗体
si:ch211-158b22.3 抗体
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