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PAD4 产品

(Peptidyl Arginine Deiminase, Type IV (PADI4))

Categories

This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. [provided by RefSeq, Jul 2008].

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Featured PAD4 Categories

PAD4 抗体

High quality antibodies with extensive validation data.

PAD4 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PAD4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PAD4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, IHC (p), FACS
Validations
  • (13)
Cat. No. ABIN1500017
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, ICC, IHC (p), ChIP
Validations
  • (1)
  • (5)
Cat. No. ABIN2856939
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN7258978
Quantity 200 μL
Datasheet Datasheet

Recommended PAD4 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958452
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973466
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975695
Quantity 96 tests
Datasheet Datasheet

Recommended PAD4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313883
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313881
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7275399
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PAD4 Products

Li, Lin, Deng, Strnad, Bernabei, Vogl, Burke, Nefedova: "A Novel Peptidylarginine Deiminase 4 (PAD4) Inhibitor BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma." in: Molecular cancer therapeutics, Vol. 19, Issue 7, pp. 1530-1538, (2020) (PubMed).

Vejlstrup, Møller, Nielsen, Damgaard: "Release of active peptidylarginine deiminase into the circulation during acute inflammation induced by coronary artery bypass surgery." in: Journal of inflammation research, Vol. 12, pp. 137-144, (2019) (PubMed).

Sur Chowdhury, Giaglis, Walker, Buser, Hahn, Hasler: "Enhanced neutrophil extracellular trap generation in rheumatoid arthritis: analysis of underlying signal transduction pathways and potential diagnostic utility." in: Arthritis research & therapy, Vol. 16, Issue 3, pp. R122, (2014) (PubMed).

Christophorou, Castelo-Branco, Halley-Stott, Oliveira, Loos, Radzisheuskaya, Mowen, Bertone, Silva, Zernicka-Goetz, Nielsen, Gurdon, Kouzarides: "Citrullination regulates pluripotency and histone H1 binding to chromatin." in: Nature, Vol. 507, Issue 7490, pp. 104-8, (2014) (PubMed).

Baka, Barta, Losonczy, Krenács, Pápay, Szarka, Sármay, Babos, Magyar, Géher, Buzás, Nagy: "Specific expression of PAD4 and citrullinated proteins in lung cancer is not associated with anti-CCP antibody production." in: International immunology, Vol. 23, Issue 6, pp. 405-14, (2011) (PubMed).

Liu, Mani, Davis, Sarrafzadegan, Kavathas, Mani: "Mutation in EGFP domain of LDL receptor-related protein 6 impairs cellular LDL clearance." in: Circulation research, Vol. 103, Issue 11, pp. 1280-8, (2008) (PubMed).

Costenbader, Chang, De Vivo, Plenge, Karlson: "Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking." in: Arthritis research & therapy, Vol. 10, Issue 3, pp. R52, (2008) (PubMed).

Nakayama-Hamada, Suzuki, Kubota, Takazawa, Ohsaka, Kawaida, Ono, Kasuya, Furukawa, Yamada, Yamamoto: "Comparison of enzymatic properties between hPADI2 and hPADI4." in: Biochemical and biophysical research communications, Vol. 327, Issue 1, pp. 192-200, (2005) (PubMed).

Wang, Wysocka, Sayegh, Lee, Perlin, Leonelli, Sonbuchner, McDonald, Cook, Dou, Roeder, Clarke, Stallcup, Allis, Coonrod: "Human PAD4 regulates histone arginine methylation levels via demethylimination." in: Science (New York, N.Y.), Vol. 306, Issue 5694, pp. 279-83, (2004) (PubMed).

Barton, Bowes, Eyre, Spreckley, Hinks, John, Worthington: "A functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population." in: Arthritis and rheumatism, Vol. 50, Issue 4, pp. 1117-21, (2004) (PubMed).

Synonyms and alternative names related to PAD4

peptidyl arginine deiminase 4 (PADI4), peptidyl arginine deiminase, type IV (Padi4), peptidyl arginine deiminase 4 (Padi4), PAD, PAD4, Pad4, PADI5, PDI4, Pdi4, PDI5

Protein level used designations for PAD4

  • peptidyl arginine deiminase, type IV
  • protein-arginine deiminase type-4-like
  • HL-60 PAD
  • PADI-H protein
  • peptidyl arginine deiminase, type V
  • protein-arginine deiminase type IV
  • protein-arginine deiminase type-4
  • PAD type IV
  • peptidylarginine deiminase IV
  • PAD-R4
  • peptidyl arginine deiminase, type 4
  • peptidylarginine deiminase type alpha
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