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PACS1 产品

(phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

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This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008].

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PACS1 抗体

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Synonyms and alternative names related to PACS1

phosphofurin acidic cluster sorting protein 1 (PACS1), phosphofurin acidic cluster sorting protein 1 (Pacs1), AI325977, MRD17, Pacs-1

Protein level used designations for PACS1

  • PACS-1
  • cytosolic sorting protein PACS-1
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