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OTU Domain, Ubiquitin Aldehyde Binding 1 产品

(OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

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Featured OTU Domain, Ubiquitin Aldehyde Binding 1 Categories

OTU Domain, Ubiquitin Aldehyde Binding 1 抗体

High quality antibodies with extensive validation data.

OTU Domain, Ubiquitin Aldehyde Binding 1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended OTU Domain, Ubiquitin Aldehyde Binding 1 抗体

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Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IHC (p), FACS
Validations
  • (12)
Cat. No. ABIN1499930
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IHC (p)
Validations
  • (11)
Cat. No. ABIN1499932
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (10)
Cat. No. ABIN1499933
Quantity 100 μL
Datasheet Datasheet

Recommended OTU Domain, Ubiquitin Aldehyde Binding 1 蛋白

Product
Reactivity
Source
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Cat. No.
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Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313747
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7197259
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7386143
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our OTU Domain, Ubiquitin Aldehyde Binding 1 Products

Wang, Mulas, Yi, Brunn, Nishanth, Just, Waisman, Brück, Deckert, Schlüter: "OTUB1 inhibits CNS autoimmunity by preventing IFN-γ-induced hyperactivation of astrocytes." in: The EMBO journal, Vol. 38, Issue 10, (2019) (PubMed).

Edelmann, Kramer, Altun, Kessler: "Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion." in: The FEBS journal, Vol. 277, Issue 11, pp. 2515-30, (2010) (PubMed).

Juris, Shah, Shokat, Dixon, Vacratsis: "Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry." in: FEBS letters, Vol. 580, Issue 1, pp. 179-83, (2006) (PubMed).

Synonyms and alternative names related to OTU Domain, Ubiquitin Aldehyde Binding 1

OTU deubiquitinase, ubiquitin aldehyde binding 1 (OTUB1), OTU domain, ubiquitin aldehyde binding 1 (Otub1), OTU deubiquitinase, ubiquitin aldehyde binding 1 (Otub1), OTU deubiquitinase, ubiquitin aldehyde binding 1b (otub1b), OTU deubiquitinase, ubiquitin aldehyde binding 1 L homeolog (otub1.L), OTU domain, ubiquitin aldehyde binding 1 (otub1), OTU domain, ubiquitin aldehyde binding 1 (OTUB1), similar to HSPC263 (RGD1565010), OTU deubiquitinase, ubiquitin aldehyde binding 1a (otub1a), AI850305, fa19h07, fb17f04, MGC131231, OTB1, OTU1, otub1, otub1l, wu:fa19h07, wu:fb17f04, zgc:92685, zgc:92839

Protein level used designations for OTU Domain, Ubiquitin Aldehyde Binding 1

  • OTU domain-containing ubiquitin aldehyde-binding protein 1
  • OTU-domain Ubal-binding 1
  • deubiquitinating enzyme OTUB1
  • otubain-1
  • ubiquitin thioesterase OTUB1
  • ubiquitin-specific protease otubain 1
  • ubiquitin-specific-processing protease OTUB1
  • otubain 1
  • OTU domain, ubiquitin aldehyde binding 1
  • Ubiquitin thioesterase OTUB1
  • ubiquitin thioesterase otub1
  • OTU deubiquitinase, ubiquitin aldehyde binding 1a
  • OTU domain, ubiquitin aldehyde binding 1, like
  • OTU domain, ubiquitin aldehyde binding 1a
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