ORC2 产品
(Origin Recognition Complex Subunit 2 (ORC2))
Categories
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate. [provided by RefSeq, Oct 2010].
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Featured ORC2 Categories
ORC2 抗体
High quality antibodies with extensive validation data.
ORC2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
ORC2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ORC2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN562076
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (1)
- (1)
Cat. No.
ABIN108579
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN2855601
Quantity
100 μL
Datasheet
Datasheet
Recommended ORC2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1146513
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1146514
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1146515
Quantity
96 tests
Datasheet
Datasheet
Recommended ORC2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313650
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094298
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3122769
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ORC2 Products
: "SLFN11 Blocks Stressed Replication Forks Independently of ATR." in: Molecular cell, Vol. 69, Issue 3, pp. 371-384.e6, (2019) (PubMed).: "RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer." in: Translational oncology, Vol. 4, Issue 4, pp. 212-21, (2011) (PubMed).
: "A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes." in: The Journal of biological chemistry, Vol. 282, Issue 31, pp. 22721-30, (2007) (PubMed).
: "Identification of HsORC4, a member of the human origin of replication recognition complex." in: The Journal of biological chemistry, Vol. 272, Issue 45, pp. 28247-51, (1997) (PubMed).
: "Mouse and human homologues of the yeast origin of replication recognition complex subunit ORC2 and chromosomal localization of the cognate human gene ORC2L." in: Genomics, Vol. 31, Issue 1, pp. 119-22, (1996) (PubMed).
Synonyms and alternative names related to ORC2
Origin recognition complex subunit 2 (Orc2), origin recognition complex second largest subunit 2 (ORC2), origin recognition complex subunit 2 (ORC2), origin recognition complex, subunit 2 (Orc2), origin recognition complex subunit 2 S homeolog (orc2.S), Origin recognition complex subunit 2 (orc-2), ATORC2, AU041563, CG3041, Dmel\\CG3041, DmORC 2, DmORC2, DmOrc2, DmOrc2p, F13M22.6, F13M22_6, fs(3)293, fs(3)293-19, k43, l(3)88Ab, l(3)A5, l(3)dsl5, l(3)K43, l(3)k43, l(3)SG44, ORC, Orc-2, ORC2, orc2, orc2-a, ORC2L, Orc2l, orc2l, Orc2p, ORIGIN RECOGNITION COMPLEX SECOND LARGEST SUBUNIT 2, origin recognition complex second largest subunit 2, rDmORC, xorc2Protein level used designations for ORC2
- CG3041-PA
- Orc2-PA
- lethal(3)88Ab
- origin recognition complex
- origin recognition complex subunit 2
- origin recognition complex protein 2 homolog
- origin recognition complex, subunit 2 homolog
- origin recognition complex, subunit 2-like
- origin recognition complex subunit 2 homolog
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