ORC1 抗体
(Origin Recognition Complex, Subunit 1 (ORC1L))
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
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ORC1 抗体 by 适用
Find ORC1 抗体 for a variety of species such as anti-Human ORC1, anti-Mouse ORC1, anti-Rat ORC1. The species listed below are among those available. Click on a link to go to the corresponding products.
ORC1 抗体 by 应用范围
Find ORC1 抗体 validated for a specific application such as WB, IF (p), ELISA, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
ORC1 抗体 by 抗体来源
Find ORC1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
ORC1 抗体 by 抗原表位
Find ORC1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
ORC1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal ORC1 抗体. Click on a link to go to the corresponding products.
ORC1 抗体 by 克隆
Find ORC1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular ORC1 抗体
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
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Cat. No.
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Quantity
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Datasheet
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Application
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Datasheet
Datasheet
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
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Application
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
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Application
WB, IF (p), IHC (p)
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Cat. No.
ABIN1713877
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC (p)
Validations
Cat. No.
ABIN1700375
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
Cat. No.
ABIN1693108
Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, IF (p)
Validations
Cat. No.
ABIN1696751
Quantity
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Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p)
Validations
Cat. No.
ABIN5008041
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
Cat. No.
ABIN1694924
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IF (p)
Validations
Cat. No.
ABIN5008042
Quantity
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Datasheet
Datasheet
Latest Publications for our ORC1 抗体
: "The cyclin A centrosomal localization sequence recruits MCM5 and Orc1 to regulate centrosome reduplication." in: Journal of cell science, Vol. 123, Issue Pt 16, pp. 2743-9, (2010) (PubMed).: "Replication factors MCM2 and ORC1 interact with the histone acetyltransferase HBO1." in: The Journal of biological chemistry, Vol. 276, Issue 18, pp. 15397-408, (2001) (PubMed).
: "Human origin recognition complex binds to the region of the latent origin of DNA replication of Epstein-Barr virus." in: The EMBO journal, Vol. 20, Issue 16, pp. 4588-602, (2001) (PubMed).
Aliases for ORC1 抗体
Origin recognition complex subunit 1 (Orc1) 抗体origin recognition complex subunit 1 (Orc1) 抗体
origin recognition complex subunit 1 (ORC1) 抗体
origin recognition complex subunit 1 L homeolog (orc1.L) 抗体
origin recognition complex, subunit 1 (Orc1) 抗体
AA545195 抗体
CG10667 抗体
Dmel\\CG10667 抗体
DmORC1 抗体
DmOrc1 抗体
DmOrc1p 抗体
dORC1 抗体
HSORC1 抗体
MmORC1 抗体
ORC 抗体
ORC1 抗体
orc1 抗体
ORC1L 抗体
orc1l 抗体
Orc1l 抗体
PARC1 抗体
rDmORC 抗体
xorc1 抗体
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