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OCT4 产品

(POU Class 5 Homeobox 1 (POU5F1))

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This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6\;22)(p21\;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Mar 2010].

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Featured OCT4 Categories

OCT4 抗体

High quality antibodies with extensive validation data.

OCT4 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

OCT4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended OCT4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (6)
Cat. No. ABIN519056
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC, FACS, IP, IHC (p), IHC (fro)
Validations
  • (4)
  • (8)
Cat. No. ABIN2855068
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (6)
Cat. No. ABIN737826
Quantity 100 μL
Datasheet Datasheet

Recommended OCT4 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969467
Quantity 96 tests
Datasheet Datasheet
Reactivity Rabbit
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969465
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958699
Quantity 96 tests
Datasheet Datasheet

Recommended OCT4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124537
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124538
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315801
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our OCT4 Products

Feng, Su, Lin, Lin, Wu, Tung, Li, Shieh, Shiau: "Oct4 upregulates osteopontin via Egr1 and is associated with poor outcome in human lung cancer." in: BMC cancer, Vol. 19, Issue 1, pp. 791, (2020) (PubMed).

Khan, Vaidyanath, Suresh, Vaishnav, Kakrani, Patil, Shiras et al.: "Generation and characterization of three clones (NCCSi007A, NCCSi007B and NCCSi007C) of an integration free induced Pluripotent Stem Cell line from a patient with alcoholic liver cirrhosis of Indian ..." in: Stem cell research, Vol. 42, pp. 101678, (2020) (PubMed).

Sohni, Tan, Song, Burow, de Rooij, Laurent, Hsieh, Rabah, Hammoud, Vicini, Wilkinson: "The Neonatal and Adult Human Testis Defined at the Single-Cell Level." in: Cell reports, Vol. 26, Issue 6, pp. 1501-1517.e4, (2019) (PubMed).

Grande, Milardi, Martini, Cenci, Gulino, Mancini, Bianchi, Pontecorvi, Pierconti: "Protein Expression of PTTG-1, OCT-4, and KLF-4 in Seminoma: A Pilot Study." in: Frontiers in endocrinology, Vol. 10, pp. 619, (2019) (PubMed).

Kaufman, Skrtic: "Spatial development of gingival fibroblasts and dental pulp cells: Effect of extracellular matrix." in: Tissue & cell, Vol. 49, Issue 3, pp. 401-409, (2018) (PubMed).

Wu, Gao, Pan, Yang, Xu, Abbas, Liu, Chen, Tan, You, Ke, Zhuang, Lin, Yang, Li: "Generation of a SMO homozygous knockout human embryonic stem cell line WAe001-A-16 by CRISPR/Cas9 editing." in: Stem cell research, Vol. 27, pp. 5-9, (2018) (PubMed).

Xu, Guo, Wu, Abbas, Lai, Yuan, You, Liu, Zhuang, Wu, Xu, Chen, Yang, Pan, Li: "Generation of a GDE heterozygous mutation human embryonic stem cell line WAe001-A-14 by CRISPR/Cas9 editing." in: Stem cell research, Vol. 27, pp. 38-41, (2018) (PubMed).

Sarkar, Verma, Akhtar, Netam, Gupta, Panda, Mukherjee: "Molecular aspect of silver nanoparticles regulated embryonic development in Zebrafish (Danio rerio) by Oct-4 expression." in: Chemosphere, Vol. 206, pp. 560-567, (2018) (PubMed).

Tan, Brasch, van Schaijik, Armstrong, Marsh, Davis, Tan, Itinteang: "Expression and Localization of Cathepsins B, D, and G in Dupuytren's Disease." in: Plastic and reconstructive surgery. Global open, Vol. 6, Issue 2, pp. e1686, (2018) (PubMed).

Han, Bedarida, Ding, Somba, Lu, Wang, Song, Zou: "β-Hydroxybutyrate Prevents Vascular Senescence through hnRNP A1-Mediated Upregulation of Oct4." in: Molecular cell, Vol. 71, Issue 6, pp. 1064-1078.e5, (2018) (PubMed).

Synonyms and alternative names related to OCT4

POU class 5 homeobox 1 (POU5F1), POU domain, class 5, transcription factor 3 (pou5f3), POU class 5 homeobox 1 (Pou5f1), POU domain, class 5, transcription factor 1 (Pou5f1), cb197, chunp6868, gp-9, gp9, NF-A3, Oct-3, Oct-3/4, Oct-4, OCT3, Oct3, Oct3/4, OCT4, oct4, Oct4, OTF-3, Otf-3, Otf-4, OTF3, Otf3, Otf3-rs7, Otf3g, OTF4, Otf4, POU-2, pou2, POU5F1, spg/pou2, wu:fd18d06

Protein level used designations for OCT4

  • POU domain transcription factor OCT4
  • POU domain, class 5, transcription factor 1
  • POU-type homeodomain-containing DNA-binding protein
  • octamer-binding protein 3
  • octamer-binding protein 4
  • octamer-binding transcription factor 3
  • octamer-binding transcription factor-3
  • POU class 5 homeobox 1
  • OTF-3
  • oct-3
  • POU domain class 5 transcription factor 1
  • spg
  • etID49452.21
  • POU domain gene 2
  • spiel ohne grenzen
  • spiel-ohne-grenzen
  • spiel ohne grenzen/pou2
  • spiel-ohne-grenzen/pou2
  • octamer binding transcription factor 4
  • Octamer-binding transcription factor 3
  • oct-4
  • octamer-binding transcription factor 4
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