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NXF1 产品

(Nuclear RNA Export Factor 1 (NXF1))
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

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Featured NXF1 Categories

NXF1 抗体

High quality antibodies with extensive validation data.

NXF1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

NXF1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NXF1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6263783
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP, IF, ICC
Validations
  • (3)
Cat. No. ABIN2855276
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
  • (3)
Cat. No. ABIN2855280
Quantity 100 μL
Datasheet Datasheet

Recommended NXF1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1116233
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN511451
Quantity 96 tests
Datasheet Datasheet
Reactivity Goat
Analytical Method Competition ELISA
Validations
Cat. No. ABIN995473
Quantity 96 tests
Datasheet Datasheet

Recommended NXF1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1313263
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124215
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313265
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our NXF1 Products

Yang, Huang, Li, Su, Shih: "Nuclear export of human hepatitis B virus core protein and pregenomic RNA depends on the cellular NXF1-p15 machinery." in: PLoS ONE, Vol. 9, Issue 10, pp. e106683, (2014) (PubMed).

Bear, Tan, Zolotukhin, Tabernero, Hudson, Felber: "Identification of novel import and export signals of human TAP, the protein that binds to the constitutive transport element of the type D retrovirus mRNAs." in: Molecular and cellular biology, Vol. 19, Issue 9, pp. 6306-17, (1999) (PubMed).

Braun, Rohrbach, Schmitt, Izaurralde: "TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleus." in: The EMBO journal, Vol. 18, Issue 7, pp. 1953-65, (1999) (PubMed).

Yoon, Lee, Seol, DeMaria, Rosenzweig, Jung: "Tap: a novel cellular protein that interacts with tip of herpesvirus saimiri and induces lymphocyte aggregation." in: Immunity, Vol. 6, Issue 5, pp. 571-82, (1997) (PubMed).

Synonyms and alternative names related to NXF1

nuclear RNA export factor 1 (nxf1), nuclear RNA export factor 1 S homeolog (nxf1.S), nuclear RNA export factor 1 (NXF1), nuclear RNA export factor 1 (LOC100113601), nuclear RNA export factor 1 (Tsp_03999), nuclear RNA export factor 1 (Nxf1), Nuclear RNA export factor 1 (nxf-1), im:7156527, mex67, MEX67, Mex67, Mex67h, MGC82224, Mvb1, NXF1, tap, TAP, Tap, wu:fc12d06

Protein level used designations for NXF1

  • nuclear RNA export factor 1
  • small bristles
  • Nuclear RNA export factor 1
  • nuclear RNA export factor 1-like
  • mRNA export factor TAP
  • tip associating protein
  • tip-associated protein
  • tip-associating protein
  • Mex 67 homolog
  • modifier of vibrator 1
  • nuclear RNA export factor 1 homolog
  • tip associated protein
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