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NUMB 抗体

(Numb Homolog (NUMB))
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
NUMB 抗体  (C-Term) NUMB 抗体  (C-Term) NUMB 抗体 (C-Term) (ABIN184679)

Verified NUMB 适用: 人, 小鼠 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated

NUMB 抗体  (AA 521-640) NUMB 抗体  (AA 521-640) NUMB 抗体 (AA 521-640) (ABIN6144943)

NUMB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

NUMB 抗体  (AA 1-135) NUMB 抗体  (AA 1-135) NUMB 抗体 (AA 1-135) (ABIN563731)

NUMB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A7-A6 unconjugated

NUMB 抗体 by Grade

Find NUMB 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

NUMB 抗体 by 适用

Find NUMB 抗体 for a variety of species such as anti-Human NUMB, anti-Mouse NUMB, anti-Rat NUMB. The species listed below are among those available. Click on a link to go to the corresponding products.

NUMB 抗体 by 应用范围

Find NUMB 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

NUMB 抗体 by 抗体来源

Find NUMB 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

NUMB 抗体 by 抗原表位

Find NUMB 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

NUMB 抗体 by 克隆形成能力

Find available monoclonal or polyclonal NUMB 抗体. Click on a link to go to the corresponding products.

NUMB 抗体 by 克隆

Find NUMB 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

NUMB 抗体 by 标记

Find NUMB 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular NUMB 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, IF, FACS
Validations
  • (9)
Cat. No. ABIN184679
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN6144943
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN563731
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human, Monkey, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN1103353
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IF (cc), IF (p), ICC, IHC (fro)
Validations
  • (1)
  • (1)
Cat. No. ABIN744428
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, PLA
Validations
  • (2)
Cat. No. ABIN522098
Quantity 100 μg
Datasheet Datasheet
Reactivity Chicken, Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6263769
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN604942
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN1860074
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN1860075
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN3032082
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7165878
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN563730
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6748443
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN2743382
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our NUMB 抗体

Wang, Xiang, Liu, He, Randle, Zhang, Dongre, Sachs, Clark, Tao, Chen, Botchkarev, Xie, Dai, Clevers, Li, Livingston: "Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer." in: Cell, Vol. 178, Issue 1, pp. 135-151.e19, (2019) (PubMed).

Cesur, Eren, Eren, Ergin, Ek, Yıldız, Şirinyıldız, Gök Balcı, Ongel: "Effect of experimentally induced hypothyroidism during gestation period on activity dependent neurotrophic factor (ADNF) in newborn rat brain tissue." in: Hormone molecular biology and clinical investigation, Vol. 36, Issue 3, (2018) (PubMed).

Lenihan, Saha, Heimer-McGinn, Cryan, Feng, Young: "Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice." in: Molecular neurobiology, (2016) (PubMed).

Mah, Soloff, Hedrick, Mariani: "Atypical PKC-iota Controls Stem Cell Expansion via Regulation of the Notch Pathway." in: Stem cell reports, Vol. 5, Issue 5, pp. 866-80, (2015) (PubMed).

Li, Fu, Zhang, Zhang, Xu, Ma, Li, Song: "The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1." in: Nature medicine, Vol. 20, Issue 1, pp. 80-6, (2014) (PubMed).

Colaluca, Tosoni, Nuciforo, Senic-Matuglia, Galimberti, Viale, Pece, Di Fiore: "NUMB controls p53 tumour suppressor activity." in: Nature, Vol. 451, Issue 7174, pp. 76-80, (2008) (PubMed).

Maiorano, Favia, Pece, Resta, Maisonneuve, Di Fiore, Capodiferro, Urbani, Viale: "Prognostic implications of NUMB immunoreactivity in salivary gland carcinomas." in: International journal of immunopathology and pharmacology, Vol. 20, Issue 4, pp. 779-89, (2008) (PubMed).

Nishimura, Kaibuchi: "Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3." in: Developmental cell, Vol. 13, Issue 1, pp. 15-28, (2007) (PubMed).

Holowacz, Zeng, Lassar: "Asymmetric localization of numb in the chick somite and the influence of myogenic signals." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 235, Issue 3, pp. 633-45, (2006) (PubMed).

Sanada, Tsai: "G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors." in: Cell, Vol. 122, Issue 1, pp. 119-31, (2005) (PubMed).

Aliases for NUMB 抗体

NUMB, endocytic adaptor protein (NUMB) 抗体
numb homolog (Drosophila) (Numb) 抗体
NUMB, endocytic adaptor protein (Numb) 抗体
numb homolog (Drosophila) (numb) 抗体
C14orf41 抗体
c14_5527 抗体
Nb 抗体
S171 抗体
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