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NUAK2 产品

(NUAK Family, SNF1-Like Kinase, 2 (NUAK2))

Categories

Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95- activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1 (By similarity).

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Featured NUAK2 Categories

NUAK2 抗体

High quality antibodies with extensive validation data.

NUAK2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NUAK2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN529396
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7161746
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN3021383
Quantity 100 μL
Datasheet Datasheet

Recommended NUAK2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231595
Quantity 96 tests
Datasheet Datasheet

Recommended NUAK2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313135
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313134
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509050
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our NUAK2 Products

Gill, Christova, Zhang, Gregorieff, Zhang, Narimatsu, Song, Xiong, Couzens, Tong, Krieger, Moran, Zlotta, van der Kwast, Gingras, Sicheri, Wrana, Attisano: "A feed forward loop enforces YAP/TAZ signaling during tumorigenesis." in: Nature communications, Vol. 9, Issue 1, pp. 3510, (2018) (PubMed).

Lessard, Rivas, So, Koh, Queiroz, Hirshman, Fielding, Goodyear: "The AMPK-related kinase SNARK regulates muscle mass and myocyte survival." in: The Journal of clinical investigation, Vol. 126, Issue 2, pp. 560-70, (2016) (PubMed).

Kim, Lee, Chae, Kang, Lee, Oh, Kim, Kim, Kim: "Association between phosphorylated AMP-activated protein kinase and MAPK3/1 expression and prognosis for patients with gastric cancer." in: Oncology, Vol. 85, Issue 2, pp. 78-85, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Yamamoto, Takashima, Shintani, Yamazaki, Seguchi, Nakano, Higo, Kato, Liao, Asano, Minamino, Matsumura, Takeda, Kitakaze: "Identification of a novel substrate for TNFalpha-induced kinase NUAK2." in: Biochemical and biophysical research communications, Vol. 365, Issue 3, pp. 541-7, (2008) (PubMed).

Lefebvre, Bai, Shahmolky, Sharma, Poon, Drucker, Rosen: "Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK." in: The Biochemical journal, Vol. 355, Issue Pt 2, pp. 297-305, (2001) (PubMed).

Synonyms and alternative names related to NUAK2

NUAK family kinase 2 (NUAK2), NUAK family, SNF1-like kinase, 2 (Nuak2), NUAK family kinase 2 (Nuak2), 1200013B22Rik, 1200013b22rik, mKIAA0537, Omphk2, SNARK, Snark, UV126

Protein level used designations for NUAK2

  • NUAK family SNF1-like kinase 2
  • SNF1/AMP activated protein kinase
  • SNF1/AMP kinase-related kinase
  • omphalocele kinase 2
  • SNF1/AMP-activated protein kinase
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