NTRK3 产品
(Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
Categories
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011].
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Featured NTRK3 Categories
NTRK3 抗体
High quality antibodies with extensive validation data.
NTRK3 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
NTRK3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NTRK3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (6)
Cat. No.
ABIN7443641
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p), IF, ICC
Validations
- (11)
Cat. No.
ABIN1499842
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (5)
Cat. No.
ABIN2784511
Quantity
100 μL
Datasheet
Datasheet
Recommended NTRK3 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968903
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1116172
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
Cat. No.
ABIN5692236
Quantity
96 tests
Datasheet
Datasheet
Recommended NTRK3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313121
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7320924
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7092728
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NTRK3 Products
: "Neurotrophin-3 restores synaptic plasticity in the striatum of a mouse model of Huntington's disease." in: CNS neuroscience & therapeutics, Vol. 24, Issue 4, pp. 353-363, (2018) (PubMed).: "A small molecule TrkB/TrkC neurotrophin receptor co-activator with distinctive effects on neuronal survival and process outgrowth." in: Neuropharmacology, Vol. 110, Issue Pt A, pp. 343-61, (2016) (PubMed).
: "Expression of neurotrophic factors in injured spinal cord after transplantation of human-umbilical cord blood stem cells in rats." in: Journal of veterinary science, Vol. 17, Issue 1, pp. 97-102, (2016) (PubMed).
: "Neurotrophin signaling via TrkB and TrkC receptors promotes the growth of brain tumor-initiating cells." in: The Journal of biological chemistry, Vol. 290, Issue 6, pp. 3814-24, (2015) (PubMed).
: "Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes." in: Nature biotechnology, Vol. 33, Issue 1, pp. 89-96, (2015) (PubMed).
: "Neurotrophins regulate bone marrow stromal cell IL-6 expression through the MAPK pathway." in: PLoS ONE, Vol. 5, Issue 3, pp. e9690, (2010) (PubMed).
: "EGF and bFGF pre-treatment enhances neural specification and the response to neuronal commitment of MIAMI cells." in: Differentiation; research in biological diversity, Vol. 80, Issue 4-5, pp. 213-27, (2010) (PubMed).
: "BDNF mediated TrkB activation is a survival signal for transitional cell carcinoma cells." in: International journal of oncology, Vol. 36, Issue 6, pp. 1469-76, (2010) (PubMed).
: "TrkB antibody elicits cytotoxicity and suppresses migration/invasion of transitional cell carcinoma cells." in: International journal of oncology, Vol. 37, Issue 4, pp. 943-9, (2010) (PubMed).
: "A kinase-deficient TrkC receptor isoform activates Arf6-Rac1 signaling through the scaffold protein tamalin." in: The Journal of cell biology, Vol. 173, Issue 2, pp. 291-9, (2006) (PubMed).
Synonyms and alternative names related to NTRK3
neurotrophic receptor tyrosine kinase 3 (NTRK3), neurotrophic receptor tyrosine kinase 3 (Ntrk3), neurotrophic tyrosine kinase, receptor, type 3 (Ntrk3), AW125844, gp145(trkC), Ntrk3_tv3, TRKC, trkC, TrkCProtein level used designations for NTRK3
- ETS related protein-neurotrophic receptor tyrosine kinase fusion protein
- ETV6-NTRK3 fusion
- GP145-TrkC
- NT-3 growth factor receptor
- tyrosine kinase receptor C
- neural receptor protein-tyrosine kinase (trkC)
- trk-C
- trkC tyrosine kinase
- neurotrophin-3
- neurotrophic tyrosine kinase receptor type 3
- tyrosine kinase C receptor, TrkC receptor, high-affinity neurotrophin receptor
- gp145-trkC
- neurotrophic tyrosine kinase, receptor, type 3
- NT-3 growth factor receptor-like
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