NSMCE1 产品
(Non-SMC Element 1 Homolog (NSMCE1))
Categories
Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Has in vitro ubiquitin ligase activity in presence of NDNL2. Is involved in positive regulation of response to DNA damage stimulus.
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Featured NSMCE1 Categories
Recommended NSMCE1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN949901
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN2856490
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN7258810
Quantity
200 μL
Datasheet
Datasheet
Recommended NSMCE1 蛋白
Synonyms and alternative names related to NSMCE1
NSE1 homolog, SMC5-SMC6 complex component (nsmce1), NSE1 homolog, SMC5-SMC6 complex component (NSMCE1), NSE1 homolog, SMC5-SMC6 complex component L homeolog (nsmce1.L), NSE1 homolog, SMC5-SMC6 complex component (Nsmce1), 2510027N19Rik, NSE1, NSMCE1, RGD1307760, zgc:92777Protein level used designations for NSMCE1
- non-structural maintenance of chromosomes element 1 homolog
- non-SMC element 1 homolog (S. cerevisiae)
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