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NRF2 产品

(Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters\; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].

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Featured NRF2 Categories

NRF2 抗体

High quality antibodies with extensive validation data.

NRF2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

NRF2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NRF2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Pig, Rat
Application WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (19)
  • (7)
Cat. No. ABIN676673
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (22)
  • (5)
Cat. No. ABIN737271
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (2)
  • (7)
Cat. No. ABIN3021832
Quantity 100 μL
Datasheet Datasheet

Recommended NRF2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (2)
Cat. No. ABIN6963254
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (10)
  • (1)
Cat. No. ABIN6958230
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6962325
Quantity 96 tests
Datasheet Datasheet

Recommended NRF2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312459
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312461
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312463
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our NRF2 Products

Balaha, Alamer, Eisa, Aljohani: "Shikonin Alleviates Gentamicin-Induced Renal Injury in Rats by Targeting Renal Endocytosis, SIRT1/Nrf2/HO-1, TLR-4/NF-κB/MAPK, and PI3K/Akt Cascades." in: Antibiotics (Basel, Switzerland), Vol. 12, Issue 5, (2023) (PubMed).

Balaha, Almalki, Alahmari, Ahmed, Balaha: "AMPK/mTOR-driven autophagy & Nrf2/HO-1 cascade modulation by amentoflavone ameliorates indomethacin-induced gastric ulcer." in: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, Vol. 151, pp. 113200, (2022) (PubMed).

Tsai, Chen, Lin, Chou, Chen, Ho, Lin, Hwang: "Miconazole Contributes to NRF2 Activation by Noncanonical P62-KEAP1 Pathway in Bladder Cancer Cells." in: Drug design, development and therapy, Vol. 14, pp. 1209-1218, (2020) (PubMed).

Batubara, Astuti, Prastya, Ilmiawati, Maeda, Suzuki, Hamamoto, Takemori: "The Antiaging Effect of Active Fractions and Ent-11α-Hydroxy-15-Oxo-Kaur-16-En-19-Oic Acid Isolated from Adenostemma lavenia (L.) O. Kuntze at the Cellular Level." in: Antioxidants (Basel, Switzerland), Vol. 9, Issue 8, (2020) (PubMed).

Chou, Lin, Dzhagalov, Chen, Lin, Lin, Chen, Chen, Fu: "Vaccine adjuvant activity of a TLR4-activating synthetic glycolipid by promoting autophagy." in: Scientific reports, Vol. 10, Issue 1, pp. 8422, (2020) (PubMed).

Neitzel, Seiwert, Göder, Diehl, Weber, Nagel, Stroh, Rasenberger, Christmann, Fahrer: "Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation." in: Cells, Vol. 8, Issue 8, (2020) (PubMed).

Angulo, El Assar, Sevilleja-Ortiz, Fernández, Sánchez-Ferrer, Romero-Otero, Martínez-Salamanca, La Fuente, Rodríguez-Mañas: "Short-term pharmacological activation of Nrf2 ameliorates vascular dysfunction in aged rats and in pathological human vasculature. A potential target for therapeutic intervention." in: Redox biology, Vol. 26, pp. 101271, (2020) (PubMed).

Yang, Liu, Liu, Ta: "Inhibition of TLR2/TLR4 alleviates the Neisseria gonorrhoeae infection damage in human endometrial epithelial cells via Nrf2 and NF-Kβsignaling." in: Journal of reproductive immunology, Vol. 142, pp. 103192, (2020) (PubMed).

Fois, Sotgiu, Scano, Negri, Mellino, Zinellu, Pirina, Pintus, Carru, Mangoni, Zinellu: "Effects of Pirfenidone and Nintedanib on Markers of Systemic Oxidative Stress and Inflammation in Patients with Idiopathic Pulmonary Fibrosis: A Preliminary Report." in: Antioxidants (Basel, Switzerland), Vol. 9, Issue 11, (2020) (PubMed).

Sireesh, Dhamodharan, Ezhilarasi, Vijay, Ramkumar: "Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus." in: Scientific reports, Vol. 8, Issue 1, pp. 5126, (2019) (PubMed).

Synonyms and alternative names related to NRF2

nuclear factor, erythroid 2-like 2a (nfe2l2a), nuclear factor, erythroid 2 like 2 S homeolog (nfe2l2.S), nuclear factor, erythroid 2 like 2 (NFE2L2), nuclear factor, erythroid derived 2, like 2 (Nfe2l2), nuclear factor, erythroid 2-like 2 (Nfe2l2), AI194320, NF-E2R2, nfe2l2, Nrf2, NRF2, wu:fc15g09, wu:fj67e03

Protein level used designations for NRF2

  • Nrf2a
  • nuclear factor (erythroid-derived 2)-like 2
  • nuclear factor erythroid 2-related factor 2
  • ECH
  • NF-E2-related factor 2
  • NFE2-related factor 2
  • nuclear factor, erythroid derived 2, like 2
  • HEBP1
  • nuclear factor erythroid-derived 2-like 2
  • nrf2
  • nuclear factor erythroid 2-like 2
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