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NR2F6 产品

(Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))
Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type- specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock\; is required early in the development of the locus coeruleus (LC).

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Featured NR2F6 Categories

NR2F6 抗体

High quality antibodies with extensive validation data.

NR2F6 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

NR2F6 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NR2F6 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6257153
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7184487
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Mouse, Rat
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN6754924
Quantity 100 μL
Datasheet Datasheet

Recommended NR2F6 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648473
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648054
Quantity 96 tests
Datasheet Datasheet

Recommended NR2F6 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124214
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312970
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1989628
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our NR2F6 Products

Miyajima, Kadowaki, Fukushige, Shimizu, Semba, Yamanashi, Matsubara, Toyoshima, Yamamoto: "Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other." in: Nucleic acids research, Vol. 16, Issue 23, pp. 11057-74, (1989) (PubMed).

Synonyms and alternative names related to NR2F6

nuclear receptor subfamily 2 group F member 6 (NR2F6), nuclear receptor subfamily 2, group F, member 6 (Nr2f6), nuclear receptor subfamily 2, group F, member 6a (nr2f6a), nuclear receptor subfamily 2 group F member 6 L homeolog (nr2f6.L), nuclear receptor subfamily 2 group F member 6 (nr2f6), nuclear receptor subfamily 2, group F, member 6 (NR2F6), nuclear receptor subfamily 2 group F member 6 (Nr2f6), nuclear receptor subfamily 2, group F, member 6b (nr2f6b), AV090102, COUP(II), COUP-TF3, couptf2, EAR-2, ear-2, EAR2, ear2, ERBAL2, Erbal2, erbal2, fc94g11, NR2F6, nr2f6l, wu:fc72d04, wu:fc94g11, zgc:77259, zgc:77260

Protein level used designations for NR2F6

  • ERBA-related gene-2
  • V-erbA-related protein 2
  • nuclear receptor V-erbA-related
  • nuclear receptor subfamily 2 group F member 6
  • v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2
  • COUP transcription factor 3
  • EAR-2
  • avian erythroblastic leukemia viral (v-erb-a) oncogene homolog-like 2
  • COUPg
  • V-erbA-related protein EAR-2
  • orphan nuclear receptor EAR-2
  • ovalbumin upstream promoter gamma nuclear receptor rCOUPg
  • EAR2-A
  • chicken ovalbumin upstream promoter transcription factor 2
  • nuclear receptor subfamily 2, group F, member 6
  • EAR2-B
  • fc72d04
  • nr2f6
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