NR1H4 产品
(Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
Categories
This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].
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Featured NR1H4 Categories
NR1H4 抗体
High quality antibodies with extensive validation data.
NR1H4 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
NR1H4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NR1H4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7440740
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
- (4)
Cat. No.
ABIN523347
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN2778066
Quantity
100 μL
Datasheet
Datasheet
Recommended NR1H4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958257
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969011
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958255
Quantity
96 tests
Datasheet
Datasheet
Recommended NR1H4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312937
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312936
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7412779
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NR1H4 Products
: "D-Allulose enhances uptake of HDL-cholesterol into rat's primary hepatocyte via SR-B1." in: Cytotechnology, Vol. 72, Issue 2, pp. 295-301, (2020) (PubMed).: "Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling." in: Molecular & cellular proteomics : MCP, Vol. 18, Issue 3, pp. 520-533, (2019) (PubMed).
: "Adaptive homeostasis of the vitamin D-vitamin D nuclear receptor axis in 8-methoxypsoralen-induced hepatotoxicity." in: Toxicology and applied pharmacology, Vol. 362, pp. 150-158, (2019) (PubMed).
: "Early indications of ANIT-induced cholestatic liver injury: Alteration of hepatocyte polarization and bile acid homeostasis." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 110, pp. 1-12, (2018) (PubMed).
: "Effects of the fibrous topography-mediated macrophage phenotype transition on the recruitment of mesenchymal stem cells: An in vivo study." in: Biomaterials, Vol. 149, pp. 77-87, (2018) (PubMed).
: "Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease." in: The Journal of biological chemistry, Vol. 293, Issue 16, pp. 5956-5974, (2018) (PubMed).
: "Activated-farnesoid X receptor (FXR) expressed in human sperm alters its fertilising ability." in: Reproduction (Cambridge, England), Vol. 156, Issue 3, pp. 249-259, (2018) (PubMed).
: "Raspberry pomace alters cecal microbial activity and reduces secondary bile acids in rats fed a high-fat diet." in: The Journal of nutritional biochemistry, Vol. 46, pp. 13-20, (2017) (PubMed).
: "SRT1720 Alleviates ANIT-Induced Cholestasis in a Mouse Model." in: Frontiers in pharmacology, Vol. 8, pp. 256, (2017) (PubMed).
: "Activated farnesoid X receptor attenuates apoptosis and liver injury in autoimmune hepatitis." in: Molecular medicine reports, Vol. 12, Issue 4, pp. 5821-7, (2015) (PubMed).
Synonyms and alternative names related to NR1H4
nuclear receptor subfamily 1, group H, member 5 S homeolog (nr1h5.S), nuclear receptor subfamily 1, group H, member 4 (nr1h4), nuclear receptor subfamily 1 group H member 4 (NR1H4), nuclear receptor subfamily 1, group H, member 4 (Nr1h4), AI957360, BAR, FXR, Fxr, HRR-1, HRR1, NR1H4, RIP14, Rxrip14, zgc:92742, zgc:110190Protein level used designations for NR1H4
- nuclear receptor subfamily 1, group H, member 4
- orphan nuclear receptor FOR2
- FXRalpha
- bile acid receptor
- farnesoid X activated receptor
- bile acid receptor-like
- RXR-interacting protein 14
- farnesoid X nuclear receptor
- farnesoid X-activated receptor
- farnesol receptor HRR-1
- retinoid X receptor-interacting protein 14
- nuclear receptor subfamily 1 group H member 4
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