NOX3 产品
(NADPH Oxidase 3 (NOX3))
Categories
This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.[provided by RefSeq, May 2009].
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Featured NOX3 Categories
Recommended NOX3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC
Validations
- (2)
Cat. No.
ABIN7161009
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC
Validations
- (2)
Cat. No.
ABIN3185621
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
Cat. No.
ABIN702595
Quantity
100 μL
Datasheet
Datasheet
Recommended NOX3 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968794
Quantity
96 tests
Datasheet
Datasheet
Recommended NOX3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3118265
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3123387
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NOX3 Products
: "Targeting Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer by Inducing Epidermal Growth Factor Receptor Degradation via Methionine 790 Oxidation." in: Antioxidants & redox signaling, Vol. 24, Issue 5, pp. 263-79, (2016) (PubMed).: "Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration." in: The Journal of cell biology, Vol. 211, Issue 4, pp. 881-96, (2015) (PubMed).
: "A long-term high-fat diet increases oxidative stress, mitochondrial damage and apoptosis in the inner ear of D-galactose-induced aging rats." in: Hearing research, Vol. 287, Issue 1-2, pp. 15-24, (2012) (PubMed).
: "Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 46, pp. 12039-51, (2008) (PubMed).
: "Otoconin-90 deletion leads to imbalance but normal hearing: a comparison with other otoconia mutants." in: Neuroscience, Vol. 153, Issue 1, pp. 289-99, (2008) (PubMed).
: "Atherosclerosis is accelerated in patients with long-term well-controlled systemic lupus erythematosus (SLE)." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 385, Issue 1-2, pp. 35-42, (2007) (PubMed).
: "The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators." in: The Journal of biological chemistry, Vol. 280, Issue 24, pp. 23328-39, (2005) (PubMed).
: "Nox3 regulation by NOXO1, p47phox, and p67phox." in: The Journal of biological chemistry, Vol. 279, Issue 33, pp. 34250-5, (2004) (PubMed).
: "The vestibulo ocular reflex (VOR) in otoconia deficient head tilt (het) mutant mice versus wild type C57BL/6 mice." in: Brain research, Vol. 972, Issue 1-2, pp. 75-83, (2003) (PubMed).
: "Neurovestibular modulation of circadian and homeostatic regulation: vestibulohypothalamic connection?" in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 24, pp. 15723-8, (2002) (PubMed).
Synonyms and alternative names related to NOX3
NADPH oxidase 3 (Nox3), NADPH oxidase 3 (NOX3), NADPH oxidase 3 (nox3), GP91-3, het, MOX-2, nmf250Protein level used designations for NOX3
- head-tilt
- NADPH oxidase catalytic subunit-like 3
- gp91phox homolog 3
- mitogenic oxidase 2
- NADPH oxidase 3
- predicted NADPH oxidase-3
- NADPH oxidase 3-like
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