NOTCH2 抗体
(Notch 2 (NOTCH2))
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011].
recommended
recommended
NOTCH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
recommended
NOTCH2 抗体 by Grade
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NOTCH2 抗体 by 适用
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Popular NOTCH2 抗体
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
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Application
WB, ELISA
Validations
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Cat. No.
ABIN104899
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN3181821
Quantity
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Datasheet
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Reactivity
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WB, ChIP-seq
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Cat. No.
ABIN2854343
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
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Cat. No.
ABIN680183
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC
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Cat. No.
ABIN7187531
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
ABIN7161298
Quantity
100 μg
Datasheet
Datasheet
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Application
WB, ELISA, IHC (p), IHC (fro), ICC
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Cat. No.
ABIN7441634
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
ABIN6144736
Quantity
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Datasheet
Datasheet
Reactivity
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Cat. No.
ABIN7187530
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Datasheet
Datasheet
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Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Validations
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Cat. No.
ABIN6742309
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN5668275
Quantity
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Datasheet
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Reactivity
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Application
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Validations
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Cat. No.
ABIN3181820
Quantity
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Datasheet
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Reactivity
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Application
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Quantity
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Datasheet
Datasheet
Latest Publications for our NOTCH2 抗体
: "Potassium depletion induces cellular conversion in the outer medullary collecting duct altering Notch signaling pathway." in: Scientific reports, Vol. 10, Issue 1, pp. 5708, (2020) (PubMed).: "Protein Expression Analysis in Uterine Cervical Cancer for Potential Targets in Treatment." in: Pathology oncology research : POR, (2018) (PubMed).
: "Epistatic Association of CD14 and NOTCH2 Genetic Polymorphisms with Biliary Atresia in a Southern Chinese Population." in: Molecular therapy. Nucleic acids, Vol. 13, pp. 590-595, (2018) (PubMed).
: "RNA granule assembly and disassembly modulated by nuclear factor associated with double-stranded RNA 2 and nuclear factor 45." in: The Journal of biological chemistry, Vol. 289, Issue 30, pp. 21163-80, (2015) (PubMed).
: "Fatty acid binding protein 4 deficiency protects against oxygen-induced retinopathy in mice." in: PLoS ONE, Vol. 9, Issue 5, pp. e96253, (2015) (PubMed).
: "Interference of Notch 2 inhibits the progression of gliomas and induces cell apoptosis by induction of the cell cycle at the G0/G1 phase." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 734-8, (2014) (PubMed).
: "Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?." in: The American journal of pathology, Vol. 181, Issue 4, pp. 1236-49, (2012) (PubMed).
: "ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo." in: The Journal of experimental medicine, Vol. 207, Issue 3, pp. 623-35, (2010) (PubMed).
: "Immunolocalization of notch signaling protein molecules in a maxillary chondrosarcoma and its recurrent tumor." in: European journal of medical research, Vol. 15, Issue 10, pp. 456-60, (2010) (PubMed).
: "Notch4 overexpression in ameloblastoma correlates with the solid/multicystic phenotype." in: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, Vol. 110, Issue 2, pp. 224-33, (2010) (PubMed).
Aliases for NOTCH2 抗体
neurogenic locus notch homolog protein 2 (LOC581186) 抗体notch 2 (NOTCH2) 抗体
notch 3 (notch3) 抗体
notch 2 (Notch2) 抗体
notch 2 (notch2) 抗体
AGS2 抗体
AI853703 抗体
HJCYS 抗体
hN2 抗体
N2 抗体
notch6 抗体
sb:cb884 抗体
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